A Bridge from the Endoplasmic Reticulum to the Plasma Membrane Comes into View

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 2022 Mar 30

PMID 35353604

Authors

Ryan Mahling

Manu Ben-Johny

Affiliations

Soon will be listed here.

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References

Nakada T, Kashihara T, Komatsu M, Kojima K, Takeshita T, Yamada M . Physical interaction of junctophilin and the Ca1.1 C terminus is crucial for skeletal muscle contraction. Proc Natl Acad Sci U S A. 2018; 115(17):4507-4512. PMC: 5924888. DOI: 10.1073/pnas.1716649115. View

Takeshima H, Komazaki S, Nishi M, Iino M, Kangawa K . Junctophilins: a novel family of junctional membrane complex proteins. Mol Cell. 2000; 6(1):11-22. DOI: 10.1016/s1097-2765(00)00003-4. View

Yang Z, Panwar P, McFarlane C, Tuinte W, Campiglio M, Van Petegem F . Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations. Proc Natl Acad Sci U S A. 2022; 119(10):e2120416119. PMC: 8916002. DOI: 10.1073/pnas.2120416119. View

Franzini-Armstrong C . STUDIES OF THE TRIAD : I. Structure of the Junction in Frog Twitch Fibers. J Cell Biol. 2009; 47(2):488-99. PMC: 2108094. DOI: 10.1083/jcb.47.2.488. View

Perni S, Lavorato M, Beam K . De novo reconstitution reveals the proteins required for skeletal muscle voltage-induced Ca release. Proc Natl Acad Sci U S A. 2017; 114(52):13822-13827. PMC: 5748219. DOI: 10.1073/pnas.1716461115. View

Lehnart S, Wehrens X . The role of junctophilin proteins in cellular function. Physiol Rev. 2022; 102(3):1211-1261. PMC: 8934682. DOI: 10.1152/physrev.00024.2021. View

Jiang M, Zhang M, Howren M, Wang Y, Tan A, Balijepalli R . JPH-2 interacts with Cai-handling proteins and ion channels in dyads: Contribution to premature ventricular contraction-induced cardiomyopathy. Heart Rhythm. 2015; 13(3):743-52. PMC: 4762763. DOI: 10.1016/j.hrthm.2015.10.037. View

Sahu G, Wazen R, Colarusso P, Chen S, Zamponi G, Turner R . Junctophilin Proteins Tether a Cav1-RyR2-KCa3.1 Tripartite Complex to Regulate Neuronal Excitability. Cell Rep. 2019; 28(9):2427-2442.e6. DOI: 10.1016/j.celrep.2019.07.075. View

Bannister R . Bridging the myoplasmic gap: recent developments in skeletal muscle excitation-contraction coupling. J Muscle Res Cell Motil. 2007; 28(4-5):275-83. DOI: 10.1007/s10974-007-9118-5. View

10.

Perni S . The Builders of the Junction: Roles of Junctophilin1 and Junctophilin2 in the Assembly of the Sarcoplasmic Reticulum-Plasma Membrane Junctions in Striated Muscle. Biomolecules. 2022; 12(1). PMC: 8774113. DOI: 10.3390/biom12010109. View

11.

van Oort R, Garbino A, Wang W, Dixit S, Landstrom A, Gaur N . Disrupted junctional membrane complexes and hyperactive ryanodine receptors after acute junctophilin knockdown in mice. Circulation. 2011; 123(9):979-88. PMC: 3056402. DOI: 10.1161/CIRCULATIONAHA.110.006437. View

12.

Perni S, Beam K . Neuronal junctophilins recruit specific Ca and RyR isoforms to ER-PM junctions and functionally alter Ca2.1 and Ca2.2. Elife. 2021; 10. PMC: 8046434. DOI: 10.7554/eLife.64249. View

13.

Reynolds J, Quick A, Wang Q, Beavers D, Philippen L, Showell J . Junctophilin-2 gene therapy rescues heart failure by normalizing RyR2-mediated Ca release. Int J Cardiol. 2016; 225:371-380. PMC: 5101129. DOI: 10.1016/j.ijcard.2016.10.021. View

14.

Prakriya M, Lewis R . Store-Operated Calcium Channels. Physiol Rev. 2015; 95(4):1383-436. PMC: 4600950. DOI: 10.1152/physrev.00020.2014. View

15.

Poulet C, Sanchez-Alonso J, Swiatlowska P, Mouy F, Lucarelli C, Alvarez-Laviada A . Junctophilin-2 tethers T-tubules and recruits functional L-type calcium channels to lipid rafts in adult cardiomyocytes. Cardiovasc Res. 2020; 117(1):149-161. PMC: 7797210. DOI: 10.1093/cvr/cvaa033. View

16.

Bers D . Cardiac excitation-contraction coupling. Nature. 2002; 415(6868):198-205. DOI: 10.1038/415198a. View

17.

Dickson E . Endoplasmic Reticulum-Plasma Membrane Contacts Regulate Cellular Excitability. Adv Exp Med Biol. 2017; 997:95-109. DOI: 10.1007/978-981-10-4567-7_7. View