The Polysaccharide-peptide Complex from Mushroom Ameliorates Atherosclerosis by Modulating the LncRNA-miRNA-mRNA Axis
Overview
Chemistry
Nutritional Sciences
Physiology
Affiliations
An -glycosidic polysaccharide-peptide complex CMPS-80 was obtained from the fruiting body of . Of importance, CMPS-80 significantly ameliorated formation of atherosclerotic lesions and plasma lipid profiles in apolipoprotein E-deficient mice. Integrated informatics analysis suggested that CMPS-80 can modulate multiple lncRNA-microRNA-mRNA axes. CMPS-80 has a potential application for prevention of hyperlipidemia and atherosclerosis.
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