Successful Management of Feline Pemphigus Foliaceus with Pentoxifylline and Topical Hydrocortisone Aceponate
Overview
Affiliations
The treatment regimen for feline pemphigus foliaceus (PF), an autoimmune disease caused by auto-antibodies against proteins of the desmosome junction, usually includes high doses of oral or parenteral immunosuppressive drugs, typically glucocorticoids. This case adds to a growing body of evidence that topical hydrocortisone aceponate is effective for the treatment of feline PF, and demonstrates the practical use of a non-invasive diagnostic method for histopathology when owners refuse a biopsy to support a clinical diagnosis of PF. Finally, this case highlights an international trend of owner-initiated treatment of feline infectious peritonitis (FIP) using unlicensed, unregistered drugs.
Izydorczyk V, Pye C Can Vet J. 2024; 65(3):297-300.
PMID: 38434171 PMC: 10880387.
Hobi S, Beatty J, Sandy J, Barrs V Vet Med Sci. 2022; 8(3):937-944.
PMID: 35212177 PMC: 9122467. DOI: 10.1002/vms3.768.