The Effects of Exercise on White and Brown Adipose Tissue Cellularity, Metabolic Activity and Remodeling

Overview

Journal Front Physiol

Date 2021 Nov 19

PMID 34795599

Citations 10

Authors

Jacob D Garritson

Sihem Boudina

Affiliations

Soon will be listed here.

Abstract

Emerging evidence suggests a significant functional role of adipose tissue in maintaining whole-body metabolic health. It is well established that obesity leads to compositional and morphological changes in adipose tissue that can contribute to the development of cardiometabolic disorders. Thus, the function and size of adipocytes as well as perfusion and inflammation can significantly impact health outcomes independent of body mass index. Lifestyle interventions such as exercise can improve metabolic homeostasis and reduce the risk for developing cardiometabolic disorders. Adipose tissue displays remarkable plasticity in response to external stimuli such as dietary intervention and exercise. Here we review systemic and local effects of exercise that modulate white and brown adipose tissue cellularity, metabolic function and remodeling in humans and animals.

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