The Insulin Centennial-100 years of Milestones in Biochemistry

Overview

Journal J Biol Chem

Specialty Biochemistry

Date 2021 Oct 31

PMID 34717954

Citations 1

Authors

Alan D Attie

Qi-Qun Tang

Karin E Bornfeldt

Affiliations

Soon will be listed here.

Citing Articles

Insulin resistance and cardiovascular disease.

Kosmas C, Bousvarou M, Kostara C, Papakonstantinou E, Salamou E, Guzman E J Int Med Res. 2023; 51(3):3000605231164548.

PMID: 36994866 PMC: 10069006. DOI: 10.1177/03000605231164548.

References

Huopio H, Reimann F, Ashfield R, Komulainen J, Lenko H, Rahier J . Dominantly inherited hyperinsulinism caused by a mutation in the sulfonylurea receptor type 1. J Clin Invest. 2000; 106(7):897-906. PMC: 381424. DOI: 10.1172/JCI9804. View

Subramanian V, Rothenberg A, Gomez C, Cohen A, Garcia A, Bhattacharyya S . Perilipin A mediates the reversible binding of CGI-58 to lipid droplets in 3T3-L1 adipocytes. J Biol Chem. 2004; 279(40):42062-71. DOI: 10.1074/jbc.M407462200. View

Zhang H, Souza S, Muliro K, Kraemer F, Obin M, Greenberg A . Lipase-selective functional domains of perilipin A differentially regulate constitutive and protein kinase A-stimulated lipolysis. J Biol Chem. 2003; 278(51):51535-42. DOI: 10.1074/jbc.M309591200. View

Granneman J, Moore H, Krishnamoorthy R, Rathod M . Perilipin controls lipolysis by regulating the interactions of AB-hydrolase containing 5 (Abhd5) and adipose triglyceride lipase (Atgl). J Biol Chem. 2009; 284(50):34538-44. PMC: 2787315. DOI: 10.1074/jbc.M109.068478. View

Fralick M, Zinman B . The discovery of insulin in Toronto: beginning a 100 year journey of research and clinical achievement. Diabetologia. 2021; 64(5):947-953. DOI: 10.1007/s00125-020-05371-6. View

Abulizi A, Vatner D, Ye Z, Wang Y, Camporez J, Zhang D . Membrane-bound -1,2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout mice. J Lipid Res. 2020; 61(12):1565-1576. PMC: 7707176. DOI: 10.1194/jlr.RA119000586. View

Gloyn A, Pearson E, Antcliff J, Proks P, Bruining G, Slingerland A . Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes. N Engl J Med. 2004; 350(18):1838-49. DOI: 10.1056/NEJMoa032922. View

Bruning J, Michael M, Winnay J, Hayashi T, Horsch D, Accili D . A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance. Mol Cell. 1998; 2(5):559-69. DOI: 10.1016/s1097-2765(00)80155-0. View

Flier J, Kahn C, Roth J, Bar R . Antibodies that impair insulin receptor binding in an unusual diabetic syndrome with severe insulin resistance. Science. 1975; 190(4209):63-5. DOI: 10.1126/science.170678. View

10.

Goto Y, Sumida Y, Flanagan J, Robinson F, Simpson I, Cushman S . Effects of fluorescein isothiocyanate on insulin actions in rat adipocytes. Arch Biochem Biophys. 1992; 293(2):224-30. DOI: 10.1016/0003-9861(92)90389-e. View

11.

Thornberry N, Weber A . Discovery of JANUVIA (Sitagliptin), a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. Curr Top Med Chem. 2007; 7(6):557-68. DOI: 10.2174/156802607780091028. View

12.

Thorens B . Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1. Proc Natl Acad Sci U S A. 1992; 89(18):8641-5. PMC: 49976. DOI: 10.1073/pnas.89.18.8641. View

13.

Cushman S, Wardzala L . Potential mechanism of insulin action on glucose transport in the isolated rat adipose cell. Apparent translocation of intracellular transport systems to the plasma membrane. J Biol Chem. 1980; 255(10):4758-62. View

14.

Azpiazu I, Saltiel A, DePaoli-Roach A, Lawrence J . Regulation of both glycogen synthase and PHAS-I by insulin in rat skeletal muscle involves mitogen-activated protein kinase-independent and rapamycin-sensitive pathways. J Biol Chem. 1996; 271(9):5033-9. DOI: 10.1074/jbc.271.9.5033. View

15.

White M, Kahn C . Insulin action at a molecular level - 100 years of progress. Mol Metab. 2021; 52:101304. PMC: 8551477. DOI: 10.1016/j.molmet.2021.101304. View

16.

Schuit F, de Vos A, Farfari S, Moens K, Pipeleers D, Brun T . Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells. J Biol Chem. 1997; 272(30):18572-9. DOI: 10.1074/jbc.272.30.18572. View

17.

McLean B, Wong C, Campbell J, Hodson D, Trapp S, Drucker D . Revisiting the Complexity of GLP-1 Action from Sites of Synthesis to Receptor Activation. Endocr Rev. 2020; 42(2):101-132. PMC: 7958144. DOI: 10.1210/endrev/bnaa032. View

18.

Beer N, van de Bunt M, Colclough K, Lukacs C, Arundel P, Chik C . Discovery of a novel site regulating glucokinase activity following characterization of a new mutation causing hyperinsulinemic hypoglycemia in humans. J Biol Chem. 2011; 286(21):19118-26. PMC: 3099725. DOI: 10.1074/jbc.M111.223362. View

19.

Egan J, Greenberg A, Chang M, Londos C . Control of endogenous phosphorylation of the major cAMP-dependent protein kinase substrate in adipocytes by insulin and beta-adrenergic stimulation. J Biol Chem. 1990; 265(31):18769-75. View

20.

Kadowaki T, Bevins C, Cama A, Ojamaa K, Kadowaki H, Beitz L . Two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance. Science. 1988; 240(4853):787-90. DOI: 10.1126/science.2834824. View