New Insights into the Biology of the Emerging Tembusu Virus

Overview

Journal Pathogens

Date 2021 Aug 28

PMID 34451474

Citations 17

Authors

Rodolphe Hamel

Thipruethai Phanitchat

Sineewanlaya Wichit

Ronald Enrique Morales Vargas

Jiraporn Jaroenpool

Cheikh Tidiane Diagne

Julien Pompon

Dorothee Misse

Affiliations

Soon will be listed here.

Abstract

Reported for the first time in 1955 in Malaysia, Tembusu virus (TMUV) remained, for a long time, in the shadow of flaviviruses with human health importance such as dengue virus or Japanese encephalitis virus. However, since 2010 and the first large epidemic in duck farms in China, the threat of its emergence on a large scale in Asia or even its spillover into the human population is becoming more and more significant. This review aims to report current knowledge on TMUV from viral particle organization to the development of specific vaccines and therapeutics, with a particular focus on host-virus interactions.

Citing Articles

Assessing the effect of beta-propiolactone inactivation on the antigenicity and immunogenicity of cluster 2.1 duck Tembusu virus.

Rungprasert K, Tunterek W, Areeraksakul P, Prakairungnamthip D, Sri-In C, Techakriengkrai N Poult Sci. 2025; 104(3):104878.

PMID: 39919563 PMC: 11848462. DOI: 10.1016/j.psj.2025.104878.

Duck Tembusu virus induced mitophagy in vacuolate spermatogenic cells is mediated by PINK1-Parkin pathway.

Huang Y, Yan X, Chu X, Shi Y, Xiang J, Yang S Poult Sci. 2025; 104(2):104795.

PMID: 39823839 PMC: 11786760. DOI: 10.1016/j.psj.2025.104795.

4D-DIA-Based Quantitative Proteomic Analysis Reveals the Involvement of TRPV2 Protein in Duck Tembusu Virus Replication.

Chen J, Yang F, Lai L, Li H, Pan C, Bao X Viruses. 2025; 16(12.

PMID: 39772141 PMC: 11680370. DOI: 10.3390/v16121831.

Dynamics of immune responses following duck Tembusu virus infection in adult laying ducks reveal the effect of age-related immune variation on disease severity.

Nedumpun T, Rungprasert K, Ninvilai P, Limcharoen B, Tunterak W, Prakairungnamthip D Poult Sci. 2024; 104(2):104731.

PMID: 39740493 PMC: 11750524. DOI: 10.1016/j.psj.2024.104731.

Isolation, identification, and pathogenicity evaluation of a novel Cluster 3 Tembusu virus isolated from geese in China.

Wang X, Chen X, Ding Y, Xu P, Wang C, Wei X Poult Sci. 2024; 104(2):104684.

PMID: 39718055 PMC: 11733047. DOI: 10.1016/j.psj.2024.104684.

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