Gut Microbiota Differences According to Ultra-Processed Food Consumption in a Spanish Population

Overview

Journal Nutrients

Date 2021 Aug 27

PMID 34444870

Citations 33

Authors

Amanda Cuevas-Sierra

Fermin I Milagro

Paula Aranaz

Jose Alfredo Martinez

Jose I Riezu-Boj

Affiliations

Soon will be listed here.

Abstract

Ultra-processed foods (UPFs) consumption could affect gut microbiota diversity and profile. We aimed to evaluate the effects of UPFs on microbiota, considering the role of sex. The consumption of UPFs (using NOVA criteria) was assessed with a validated 137-item food-frequency questionnaire. Participants ( = 359) were classified into less than three servings per day ( = 96) of UPFs and more than five ( = 90). Women and men were subclassified following the same criteria. 16S rRNA sequencing was performed from DNA fecal samples, and differences in microbiota were analyzed using EdgeR. The relationship between UPFs and bacteria was assessed by Spearman correlation and comparison of tertiles of consumption. Women who consumed more than five servings/day of UPFs presented an increase in , Enterobacteriales, Bifidobacteriales and Actinobacteria and a decrease in and . , Bifidobacteriales and Actinobacteria was positively associated with pizza and Actinobacteria with industrially processed dairy in women. Men who consumed more than five servings/day presented an increase of Carnobacteriaceae, Bacteroidaceae, Peptostreptococcaceae, Bacteroidia and Bacteroidetes and a decrease of and Clostridiaceae. Bacteroidia and Bacteroidetes correlated positively with industrially processed meat. This study suggests that UPFs may affect microbiota composition differently in women and men.

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