» Articles » PMID: 32630022

Ultra-Processed Foods and Health Outcomes: A Narrative Review

Overview
Journal Nutrients
Date 2020 Jul 8
PMID 32630022
Citations 226
Authors
Affiliations
Soon will be listed here.
Abstract

The nutrition literature and authoritative reports increasingly recognise the concept of ultra-processed foods (UPF), as a descriptor of unhealthy diets. UPFs are now prevalent in diets worldwide. This review aims to identify and appraise the studies on healthy participants that investigated associations between levels of UPF consumption and health outcomes. This involved a systematic search for extant literature; integration and interpretation of findings from diverse study types, populations, health outcomes and dietary assessments; and quality appraisal. Of 43 studies reviewed, 37 found dietary UPF exposure associated with at least one adverse health outcome. Among adults, these included overweight, obesity and cardio-metabolic risks; cancer, type-2 diabetes and cardiovascular diseases; irritable bowel syndrome, depression and frailty conditions; and all-cause mortality. Among children and adolescents, these included cardio-metabolic risks and asthma. No study reported an association between UPF and beneficial health outcomes. Most findings were derived from observational studies and evidence of plausible biological mechanisms to increase confidence in the veracity of these observed associations is steadily evolving. There is now a considerable body of evidence supporting the use of UPFs as a scientific concept to assess the 'healthiness' of foods within the context of dietary patterns and to help inform the development of dietary guidelines and nutrition policy actions.

Citing Articles

Eating distractions as predictors of ultra-processed food consumption and Mediterranean diet adherence in adolescents.

Lopez-Gil J, Quiroz-Cardenas F, Montenegro-Espinosa J, Cisneros-Vasquez E, Mino C, Castillo-Minaca M Sci Rep. 2025; 15(1):7579.

PMID: 40038379 PMC: 11880373. DOI: 10.1038/s41598-025-91754-x.


Ultra-processed food consumption in the central division of Fiji.

Palu A, Santos J, Coyle D, Shahid M, Crowther J, Waqa G BMC Med. 2025; 23(1):109.

PMID: 39984924 PMC: 11846173. DOI: 10.1186/s12916-025-03947-w.


Association between ultra-processed food consumption and inflammation: insights from the STANISLAS cohort.

Xia L, Girerd N, Lamiral Z, Duarte K, Merckle L, Leroy C Eur J Nutr. 2025; 64(2):94.

PMID: 39960649 DOI: 10.1007/s00394-025-03607-y.


Effectiveness of an Intervention to Prevent Ultra-Processed Foods and Added Sugar in the First Year of Life: A Multicentre Randomised Controlled Trial in Brazil.

Baratto P, Hoffman D, Valmorbida J, Leffa P, Feldens C, Vitolo M J Hum Nutr Diet. 2025; 38(1):e70022.

PMID: 39957417 PMC: 11831244. DOI: 10.1111/jhn.70022.


Alternative Protein-Based Meat and Fish Analogs by Conventional and Novel Processing Technologies: A Systematic Review and Bibliometric Analysis.

Gurbuz B, Pastrana L, Pereira R, Cerqueira M Foods. 2025; 14(3).

PMID: 39942091 PMC: 11817710. DOI: 10.3390/foods14030498.


References
1.
Ni Mhurchu C, Brown R, Jiang Y, Eyles H, Dunford E, Neal B . Nutrient profile of 23 596 packaged supermarket foods and non-alcoholic beverages in Australia and New Zealand. Public Health Nutr. 2015; 19(3):401-8. PMC: 10271178. DOI: 10.1017/S1368980015000968. View

2.
Martinez Steele E, Popkin B, Swinburn B, Monteiro C . The share of ultra-processed foods and the overall nutritional quality of diets in the US: evidence from a nationally representative cross-sectional study. Popul Health Metr. 2017; 15(1):6. PMC: 5307821. DOI: 10.1186/s12963-017-0119-3. View

3.
Tavares L, Fonseca S, Rosa M, Yokoo E . Relationship between ultra-processed foods and metabolic syndrome in adolescents from a Brazilian Family Doctor Program. Public Health Nutr. 2011; 15(1):82-7. DOI: 10.1017/S1368980011001571. View

4.
Vale D, Morais C, Campos Pedrosa L, Fernandes Ferreira M, da Costa Oliveira A, Lyra C . Spatial correlation between excess weight, purchase of ultra-processed foods, and human development in Brazil. Cien Saude Colet. 2019; 24(3):983-996. DOI: 10.1590/1413-81232018243.35182016. View

5.
Monteiro C, Mondini L, Costa R . [Changes in composition and appropriate nutrition of family diet in the metropolitan areas of Brazil (1988-1996)]. Rev Saude Publica. 2000; 34(3):251-8. DOI: 10.1590/s0034-89102000000300007. View