The Role of Ultra-processed Food Consumption in Protein-energy Wasting and Sarcopenia Development in Patients with Chronic Kidney Diseases

Overview

Journal BMC Nephrol

Publisher Biomed Central

Specialty Nephrology

Date 2024 Jan 3

PMID 38172690

Authors

Zainab Shateri

Sevda Eskandarzadeh

Mehran Nouri

Shahrokh Ezzatzadegan Jahromi

Fatemeh Mansouri

Siavash Babajafari

Affiliations

Soon will be listed here.

Abstract

Background: The effect of ultra-processed foods (UPFs) on chronic kidney disease (CKD) has been studied in some studies. The present study aimed to investigate the association between UPF consumption and the risk of protein-energy wasting (PEW) and sarcopenia in patients with CKD in the Iranian population.

Methods: The current cross-sectional study included 110 patients with CKD referred to two clinics in Shiraz, Iran. The International Society of Renal Nutrition and Metabolism (ISRNM) criteria and the Asian Working Group for Sarcopenia (AWGS) guideline were considered for the diagnosis of PEW and sarcopenia, respectively. The valid semi-quantitative food frequency questionnaire was used to assess participants' dietary intake. The logistic regression was used to examine the association of UPFs with PEW and sarcopenia.

Results: We observed no significant association between sarcopenia and PEW with UPFs in the crude model. After adjusting for confounders, we observed a significantly higher odds of sarcopenia in the upper versus lower median of UPF intake (odds ratio (OR) = 3.59, 95% confidence interval (CI): 1.02-12.62, P = 0.046).

Conclusions: Our findings suggest a positive relationship between UPF intake and sarcopenia among CKD patients. Therefore, reducing the intake of UPFs may decrease the odds of sarcopenia in patients suffering from CKD.

Citing Articles

Association between pro-vegetarian dietary pattern and the risk of protein-energy wasting and sarcopenia in patients with chronic kidney disease.

Mansouri F, Shateri Z, Jahromi S, Mahmudi-Zadeh M, Nouri M, Babajafari S J Health Popul Nutr. 2024; 43(1):110.

PMID: 39085942 PMC: 11293009. DOI: 10.1186/s41043-024-00606-3.

References

Apetrii M, Timofte D, Voroneanu L, Covic A . Nutrition in Chronic Kidney Disease-The Role of Proteins and Specific Diets. Nutrients. 2021; 13(3). PMC: 7999704. DOI: 10.3390/nu13030956. View

Gracia-Iguacel C, Gonzalez-Parra E, Mahillo I, Ortiz A . Criteria for classification of protein-energy wasting in dialysis patients: impact on prevalence. Br J Nutr. 2019; 121(11):1271-1278. DOI: 10.1017/S0007114519000400. View

Sabatino A, Regolisti G, Brusasco I, Cabassi A, Morabito S, Fiaccadori E . Alterations of intestinal barrier and microbiota in chronic kidney disease. Nephrol Dial Transplant. 2014; 30(6):924-33. DOI: 10.1093/ndt/gfu287. View

Abreu I, Nascimento L, Lima R, Santos C . Children and adolescents with chronic kidney disease in haemodialysis: perception of professionals. Rev Bras Enferm. 2015; 68(6):1020-6. DOI: 10.1590/0034-7167.2015680604i. View

Drewnowski A . Nutrition transition and global dietary trends. Nutrition. 2000; 16(7-8):486-7. DOI: 10.1016/s0899-9007(00)00295-1. View

Avesani C, Cuppari L, Nerbass F, Lindholm B, Stenvinkel P . Ultraprocessed foods and chronic kidney disease-double trouble. Clin Kidney J. 2023; 16(11):1723-1736. PMC: 10616474. DOI: 10.1093/ckj/sfad103. View

Hanna R, Ghobry L, Wassef O, Rhee C, Kalantar-Zadeh K . A Practical Approach to Nutrition, Protein-Energy Wasting, Sarcopenia, and Cachexia in Patients with Chronic Kidney Disease. Blood Purif. 2019; 49(1-2):202-211. DOI: 10.1159/000504240. View

Kityo A, Lee S . The Intake of Ultra-Processed Foods and Prevalence of Chronic Kidney Disease: The Health Examinees Study. Nutrients. 2022; 14(17). PMC: 9460585. DOI: 10.3390/nu14173548. View

Montero-Salazar H, Donat-Vargas C, Moreno-Franco B, Sandoval-Insausti H, Civeira F, Laclaustra M . High consumption of ultra-processed food may double the risk of subclinical coronary atherosclerosis: the Aragon Workers' Health Study (AWHS). BMC Med. 2020; 18(1):235. PMC: 7425006. DOI: 10.1186/s12916-020-01678-8. View

10.

Lane K, Davies I, Darabi Z, Ghayour-Mobarhan M, Khayyatzadeh S, Mazidi M . The Association between Ultra-Processed Foods, Quality of Life and Insomnia among Adolescent Girls in Northeastern Iran. Int J Environ Res Public Health. 2022; 19(10). PMC: 9141842. DOI: 10.3390/ijerph19106338. View

11.

Schaap L, Pluijm S, Deeg D, Harris T, Kritchevsky S, Newman A . Higher inflammatory marker levels in older persons: associations with 5-year change in muscle mass and muscle strength. J Gerontol A Biol Sci Med Sci. 2009; 64(11):1183-9. PMC: 2759573. DOI: 10.1093/gerona/glp097. View

12.

Rey-Garcia J, Donat-Vargas C, Sandoval-Insausti H, Bayan-Bravo A, Moreno-Franco B, Banegas J . Ultra-Processed Food Consumption is Associated with Renal Function Decline in Older Adults: A Prospective Cohort Study. Nutrients. 2021; 13(2). PMC: 7912450. DOI: 10.3390/nu13020428. View

13.

Martini D, Godos J, Bonaccio M, Vitaglione P, Grosso G . Ultra-Processed Foods and Nutritional Dietary Profile: A Meta-Analysis of Nationally Representative Samples. Nutrients. 2021; 13(10). PMC: 8538030. DOI: 10.3390/nu13103390. View

14.

Monteiro C, Cannon G, Levy R, Moubarac J, Louzada M, Rauber F . Ultra-processed foods: what they are and how to identify them. Public Health Nutr. 2019; 22(5):936-941. PMC: 10260459. DOI: 10.1017/S1368980018003762. View

15.

Cuevas-Sierra A, Milagro F, Aranaz P, Martinez J, Riezu-Boj J . Gut Microbiota Differences According to Ultra-Processed Food Consumption in a Spanish Population. Nutrients. 2021; 13(8). PMC: 8398738. DOI: 10.3390/nu13082710. View

16.

Chen L, Woo J, Assantachai P, Auyeung T, Chou M, Iijima K . Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment. J Am Med Dir Assoc. 2020; 21(3):300-307.e2. DOI: 10.1016/j.jamda.2019.12.012. View

17.

Baker P, Friel S . Food systems transformations, ultra-processed food markets and the nutrition transition in Asia. Global Health. 2016; 12(1):80. PMC: 5135831. DOI: 10.1186/s12992-016-0223-3. View

18.

Sabatino A, Cuppari L, Stenvinkel P, Lindholm B, Avesani C . Sarcopenia in chronic kidney disease: what have we learned so far?. J Nephrol. 2020; 34(4):1347-1372. PMC: 8357704. DOI: 10.1007/s40620-020-00840-y. View

19.

Snelson M, Tan S, Clarke R, de Pasquale C, Thallas-Bonke V, Nguyen T . Processed foods drive intestinal barrier permeability and microvascular diseases. Sci Adv. 2021; 7(14). PMC: 8011970. DOI: 10.1126/sciadv.abe4841. View

20.

Menezes C, Magalhaes L, Silva J, Lago R, Gomes A, Ladeia A . Ultra-Processed Food Consumption Is Related to Higher Trans Fatty Acids, Sugar Intake, and Micronutrient-Impaired Status in Schoolchildren of Bahia, Brazil. Nutrients. 2023; 15(2). PMC: 9863107. DOI: 10.3390/nu15020381. View