Apple Allergy: Causes and Factors Influencing Fruits Allergenic Properties-Review

Overview

Journal Clin Transl Allergy

Publisher Wiley

Specialty Allergy & Immunology

Date 2021 Jun 14

PMID 34123364

Citations 6

Authors

Aleksandra Siekierzynska

Dorota Piasecka-Kwiatkowska

Aleksander Myszka

Marta Burzynska

Barbara Sozanska

Tomasz Sozanski

Affiliations

Soon will be listed here.

Abstract

Background: Apple tree fruits ( × Borkh.) are a rich source of nutrients and nutraceuticals and are recommended as a part of the healthy, staple diet. However, apples could be also the cause of allergies including severe reactions. Allergies to fruits like apples are predominantly associated with pollinosis. In North and Central Europe, sensitisation to apples is caused mainly by cross-reactive birch pollen aeroallergen, whereas in the Mediterranean area of Europe, apple allergy is mostly associated with allergies to peach. The allergenicity of apples differ across cultivars but only a few varieties were studied. Some factors changing apples allergenicity were identified, including unmodifiable and potentially modifiable factors for example cultivation method, ripening stage and storage conditions.

Aim: This review presents current knowledge about the molecular basis of apple allergenicity and factors influencing its level.

Conclusions: Selecting cultivars with low potential of allergenicity, removing apple peel and heat treatment could reduce the risk of severe allergy reaction incidence and presumably can be used in birch pollen immunotherapy.

Citing Articles

Suitability of Selected Apple Varieties for People with Allergies and Diabetes.

Aninowski M, Leszczynska J, Bonikowski R, Ponder A, Hallmann E, Grzyb M Nutrients. 2024; 16(13).

PMID: 38999855 PMC: 11243659. DOI: 10.3390/nu16132109.

Profiles of apple allergen components and its diagnostic value in Northern China.

Wang X, Chen L, Lan T, Wang H, Wang X Front Med (Lausanne). 2024; 11:1388766.

PMID: 38938380 PMC: 11208676. DOI: 10.3389/fmed.2024.1388766.

Profiles of Birch Allergen Component Sensitization and Its Association with Pollen Food Allergy Syndrome in Northern China.

Wang X, Chen L, Ding J, Wang H, Wang X J Asthma Allergy. 2023; 16:1241-1250.

PMID: 38022747 PMC: 10656847. DOI: 10.2147/JAA.S427764.

Essential Oils as Multicomponent Mixtures and Their Potential for Human Health and Well-Being.

Bunse M, Daniels R, Grundemann C, Heilmann J, Kammerer D, Keusgen M Front Pharmacol. 2022; 13:956541.

PMID: 36091825 PMC: 9449585. DOI: 10.3389/fphar.2022.956541.

New Mass Spectrometric Approach to Quantify the Major Isoallergens of the Apple Allergen Mal d 1.

A H Kaeswurm J, Straub L, Klussmann A, Brockmeyer J, Buchweitz M J Agric Food Chem. 2022; 70(37):11813-11822.

PMID: 36074755 PMC: 9504475. DOI: 10.1021/acs.jafc.2c03745.

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