Human Embryo Research, Stem Cell-derived Embryo Models and In vitro Gametogenesis: Considerations Leading to the Revised ISSCR Guidelines

Overview

Journal Stem Cell Reports

Publisher Cell Press

Specialty Cell Biology

Date 2021 May 28

PMID 34048690

Citations 31

Authors

Amander T Clark

Ali Brivanlou

Jianping Fu

Kazuto Kato

Debra Mathews

Kathy K Niakan

Nicolas Rivron

Mitinori Saitou

Azim Surani

Fuchou Tang

Janet Rossant

Affiliations

Soon will be listed here.

Abstract

The ISSCR Guidelines for Stem Cell Research and Clinical Translation were last revised in 2016. Since then, rapid progress has been made in research areas related to in vitro culture of human embryos, creation of stem cell-based embryo models, and in vitro gametogenesis. Therefore, a working group of international experts was convened to review the oversight process and provide an update to the guidelines. This report captures the discussion and summarizes the major recommendations made by this working group, with a specific emphasis on updating the categories of review and engagement with the specialized scientific and ethical oversight process.

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