Phase-stabilized Complex-decorrelation Angiography

Overview

Journal Biomed Opt Express

Specialty Radiology

Date 2021 May 17

PMID 33996238

Citations 5

Authors

Xiang Wei

Tristan T Hormel

Yali Jia

Affiliations

Soon will be listed here.

Abstract

In this study, we developed a novel phase-stabilized complex-decorrelation (PSCD) optical coherence tomography (OCT) angiography (OCTA) method that can generate high quality OCTA images. This method has been validated using three different types of OCT systems and compared with conventional complex- and amplitude-based OCTA algorithms. Our results suggest that in combination with a pre-processing phase stabilization method, the PSCD method is insensitive to bulk motion phase shifts, less dependent on OCT reflectance than conventional complex methods and demonstrates extended dynamic range of flow signal, in contrast to other two methods.

Citing Articles

Advances in OCT Angiography.

Hormel T, Huang D, Jia Y Transl Vis Sci Technol. 2025; 14(3):6.

PMID: 40052848 PMC: 11905608. DOI: 10.1167/tvst.14.3.6.

Wide-field OCT angiography for non-human primate retinal imaging.

Wei X, Hormel T, Renner L, Neuringer M, Jia Y Biomed Opt Express. 2024; 15(8):4642-4654.

PMID: 39346973 PMC: 11427193. DOI: 10.1364/BOE.525839.

Visualizing features with wide-field volumetric OCT angiography.

Hormel T, Liang G, Wei X, Guo Y, Gao M, Wang J Opt Express. 2024; 32(6):10329-10347.

PMID: 38571248 PMC: 11018334. DOI: 10.1364/OE.510640.

Feasibility of deep learning-based polarization-sensitive optical coherence tomography angiography for imaging cutaneous microvasculature.

Pan M, Wang Y, Gong P, Wang Q, Cense B Biomed Opt Express. 2023; 14(8):3856-3870.

PMID: 37799704 PMC: 10549757. DOI: 10.1364/BOE.488822.

Widefield Optical Coherence Tomography in Pediatric Retina: A Case Series of Intraoperative Applications Using a Prototype Handheld Device.

Nguyen T, Ni S, Liang G, Khan S, Wei X, Skalet A Front Med (Lausanne). 2022; 9:860371.

PMID: 35860728 PMC: 9289179. DOI: 10.3389/fmed.2022.860371.

References

de Carlo T, Romano A, Waheed N, Duker J . A review of optical coherence tomography angiography (OCTA). Int J Retina Vitreous. 2016; 1:5. PMC: 5066513. DOI: 10.1186/s40942-015-0005-8. View

An L, Wang R . In vivo volumetric imaging of vascular perfusion within human retina and choroids with optical micro-angiography. Opt Express. 2008; 16(15):11438-52. DOI: 10.1364/oe.16.011438. View

Braaf B, Vermeer K, Sicam V, van Zeeburg E, van Meurs J, de Boer J . Phase-stabilized optical frequency domain imaging at 1-µm for the measurement of blood flow in the human choroid. Opt Express. 2011; 19(21):20886-903. DOI: 10.1364/OE.19.020886. View

Chen T, Cense B, Pierce M, Nassif N, Park B, Yun S . Spectral domain optical coherence tomography: ultra-high speed, ultra-high resolution ophthalmic imaging. Arch Ophthalmol. 2005; 123(12):1715-20. DOI: 10.1001/archopht.123.12.1715. View

Choi W, Moult E, Waheed N, Adhi M, Lee B, Lu C . Ultrahigh-Speed, Swept-Source Optical Coherence Tomography Angiography in Nonexudative Age-Related Macular Degeneration with Geographic Atrophy. Ophthalmology. 2015; 122(12):2532-44. PMC: 4658257. DOI: 10.1016/j.ophtha.2015.08.029. View

Ploner S, Moult E, Choi W, Waheed N, Lee B, Novais E . TOWARD QUANTITATIVE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY: Visualizing Blood Flow Speeds in Ocular Pathology Using Variable Interscan Time Analysis. Retina. 2016; 36 Suppl 1:S118-S126. PMC: 5193243. DOI: 10.1097/IAE.0000000000001328. View

Wei X, Hormel T, Guo Y, Jia Y . 75-degree non-mydriatic single-volume optical coherence tomographic angiography. Biomed Opt Express. 2019; 10(12):6286-6295. PMC: 6913399. DOI: 10.1364/BOE.10.006286. View

Mariampillai A, Leung M, Jarvi M, Standish B, Lee K, Wilson B . Optimized speckle variance OCT imaging of microvasculature. Opt Lett. 2010; 35(8):1257-9. DOI: 10.1364/OL.35.001257. View

Fingler J, Schwartz D, Yang C, Fraser S . Mobility and transverse flow visualization using phase variance contrast with spectral domain optical coherence tomography. Opt Express. 2009; 15(20):12636-53. DOI: 10.1364/oe.15.012636. View

10.

Pi S, Camino A, Cepurna W, Wei X, Zhang M, Huang D . Automated spectroscopic retinal oximetry with visible-light optical coherence tomography. Biomed Opt Express. 2018; 9(5):2056-2067. PMC: 5946770. DOI: 10.1364/BOE.9.002056. View

11.

Kim S, Raphael P, Oghalai J, Applegate B . High-speed spectral calibration by complex FIR filter in phase-sensitive optical coherence tomography. Biomed Opt Express. 2016; 7(4):1430-44. PMC: 4929652. DOI: 10.1364/BOE.7.001430. View

12.

Guo Y, Camino A, Zhang M, Wang J, Huang D, Hwang T . Automated segmentation of retinal layer boundaries and capillary plexuses in wide-field optical coherence tomographic angiography. Biomed Opt Express. 2019; 9(9):4429-4442. PMC: 6157796. DOI: 10.1364/BOE.9.004429. View

13.

Liu G, Tan O, Gao S, Pechauer A, Lee B, Lu C . Postprocessing algorithms to minimize fixed-pattern artifact and reduce trigger jitter in swept source optical coherence tomography. Opt Express. 2015; 23(8):9824-34. PMC: 4523376. DOI: 10.1364/OE.23.009824. View

14.

Wei X, Hormel T, Guo Y, Hwang T, Jia Y . High-resolution wide-field OCT angiography with a self-navigation method to correct microsaccades and blinks. Biomed Opt Express. 2020; 11(6):3234-3245. PMC: 7316026. DOI: 10.1364/BOE.390430. View

15.

Wei X, Camino A, Pi S, Cepurna W, Huang D, Morrison J . Fast and robust standard-deviation-based method for bulk motion compensation in phase-based functional OCT. Opt Lett. 2018; 43(9):2204-2207. PMC: 6411296. DOI: 10.1364/OL.43.002204. View

16.

Hormel T, Wang J, Bailey S, Hwang T, Huang D, Jia Y . Maximum value projection produces better OCT angiograms than mean value projection. Biomed Opt Express. 2019; 9(12):6412-6424. PMC: 6491019. DOI: 10.1364/BOE.9.006412. View

17.

An L, Qin J, Wang R . Ultrahigh sensitive optical microangiography for in vivo imaging of microcirculations within human skin tissue beds. Opt Express. 2010; 18(8):8220-8. PMC: 2898895. DOI: 10.1364/OE.18.008220. View

18.

Gora M, Karnowski K, Szkulmowski M, Kaluzny B, Huber R, Kowalczyk A . Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range. Opt Express. 2009; 17(17):14880-94. DOI: 10.1364/oe.17.014880. View

19.

Wei X, Hormel T, Pi S, Guo Y, Jian Y, Jia Y . High dynamic range optical coherence tomography angiography (HDR-OCTA). Biomed Opt Express. 2019; 10(7):3560-3571. PMC: 6640830. DOI: 10.1364/BOE.10.003560. View

20.

Tan B, Hosseinaee Z, Han L, Kralj O, Sorbara L, Bizheva K . 250 kHz, 1.5 µm resolution SD-OCT for cellular imaging of the human cornea. Biomed Opt Express. 2019; 9(12):6569-6583. PMC: 6490998. DOI: 10.1364/BOE.9.006569. View