A Bibliometric Analysis of Primary Aldosteronism Research From 2000 to 2020

Overview

Journal Front Endocrinol (Lausanne)

Specialty Endocrinology

Date 2021 May 14

PMID 33986730

Citations 11

Authors

Chengyuan Wang

Hongwei Jing

Zuyu Sun

Jiaxi Yao

Xinyu Zhang

Tao Liu

Ying Wu

Affiliations

Soon will be listed here.

Abstract

Thousands of papers on primary aldosteronism (PA) have been published in the last two decades. This study aimed to evaluate the research hotspots and future trends in PA research using bibliometric analysis. A total of 2,365 PA research papers between 2000 and 2020 were included. The dominant position of the United States in global PA research throughout this 20-year period was evident, and it was also the country most frequently involved in international cooperation. The University of Padua was the most productive institution and a leader in research collaboration. The Journal of Clinical Endocrinology & Metabolism was the most productive journal in terms of the number of publications on PA. Further, Mulatero P, Reincke M, Beuschlein F and Wu VC all made significant contributions to PA research. Five hotspots have been identified: (1) metabolic syndrome associated with PA; (2) molecular mechanisms of PA; (3) adrenal adenoma and adrenal cortex; (4) hypertension associated with PA; and (5) clinical monitoring parameters and diagnosis in patients with PA. Our results suggest that the molecular mechanisms of PA will remain research hotspots in the future. International collaboration is also expected to widen and deepen in the field of PA research.

Citing Articles

Research hotspots and trends of acupoint and pain based on PubMed: a bibliometric analysis.

Wu Z, Tan W, Li S, Zhang W, Lai M, Luo W Front Neurol. 2025; 15:1498576.

PMID: 39895908 PMC: 11783567. DOI: 10.3389/fneur.2024.1498576.

The role of astrocytes in Alzheimer's disease: a bibliometric analysis.

An X, He J, Bi B, Wu G, Xu J, Yu W Front Aging Neurosci. 2024; 16:1481748.

PMID: 39665038 PMC: 11632101. DOI: 10.3389/fnagi.2024.1481748.

The prevalence of metabolic syndrome in primary aldosteronism and essential hypertension: A systematic review and meta-analysis.

Sun K, Zhou C, Gong M, Zhang Y, Jiang Y, Song W J Clin Hypertens (Greenwich). 2024; 26(8):879-889.

PMID: 39037169 PMC: 11301440. DOI: 10.1111/jch.14873.

Explicating the publication paradigm by bibliometric approaches: A case of interplay between nanoscience and ferroptosis.

Huang Z, Wang W, Shu L, Guo M, Huang Y, Wu C Health Care Sci. 2024; 1(2):93-110.

PMID: 38938888 PMC: 11080826. DOI: 10.1002/hcs2.5.

Intellectual landscapes and emerging trends of non-steroidal mineralocorticoid receptor antagonists: a bibliometric and visual analysis.

Zhu L, Shi P Int Urol Nephrol. 2024; 56(9):3079-3090.

PMID: 38662266 DOI: 10.1007/s11255-024-04059-9.

References

CONN J . Presidential address. I. Painting background. II. Primary aldosteronism, a new clinical syndrome. J Lab Clin Med. 1955; 45(1):3-17. View

Rossi G, Sechi L, Giacchetti G, Ronconi V, Strazzullo P, Funder J . Primary aldosteronism: cardiovascular, renal and metabolic implications. Trends Endocrinol Metab. 2008; 19(3):88-90. DOI: 10.1016/j.tem.2008.01.006. View

Byrd J, Turcu A, Auchus R . Primary Aldosteronism: Practical Approach to Diagnosis and Management. Circulation. 2018; 138(8):823-835. PMC: 6205759. DOI: 10.1161/CIRCULATIONAHA.118.033597. View

Reincke M . Anxiety, Depression, and Impaired Quality of Life in Primary Aldosteronism: Why We Shouldn't Ignore It!. J Clin Endocrinol Metab. 2017; 103(1):1-4. DOI: 10.1210/jc.2017-02141. View

Hirsch J . An index to quantify an individual's scientific research output. Proc Natl Acad Sci U S A. 2005; 102(46):16569-72. PMC: 1283832. DOI: 10.1073/pnas.0507655102. View

Azizan E, Poulsen H, Tuluc P, Zhou J, Clausen M, Lieb A . Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. Nat Genet. 2013; 45(9):1055-60. DOI: 10.1038/ng.2716. View

Monticone S, DAscenzo F, Moretti C, Williams T, Veglio F, Gaita F . Cardiovascular events and target organ damage in primary aldosteronism compared with essential hypertension: a systematic review and meta-analysis. Lancet Diabetes Endocrinol. 2017; 6(1):41-50. DOI: 10.1016/S2213-8587(17)30319-4. View

Ono Y, Yamazaki Y, Omata K, Else T, Tomlins S, Rhayem Y . Histological Characterization of Aldosterone-producing Adrenocortical Adenomas with Different Somatic Mutations. J Clin Endocrinol Metab. 2019; 105(3). PMC: 7048684. DOI: 10.1210/clinem/dgz235. View

Velema M, de Nooijer A, Hermus A, Timmers H, Lenders J, Husson O . A disease-specific Quality of Life questionnaire for primary aldosteronism. Endocr Connect. 2019; 8(4):389-397. PMC: 6454297. DOI: 10.1530/EC-19-0026. View

10.

Sechi L, Novello M, Lapenna R, Baroselli S, Nadalini E, Colussi G . Long-term renal outcomes in patients with primary aldosteronism. JAMA. 2006; 295(22):2638-45. DOI: 10.1001/jama.295.22.2638. View

11.

Beuschlein F, Boulkroun S, Osswald A, Wieland T, Nielsen H, Lichtenauer U . Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension. Nat Genet. 2013; 45(4):440-4, 444e1-2. DOI: 10.1038/ng.2550. View

12.

Rossi G, Cesari M, Lenzini L, Seccia T . Disease monitoring of Primary Aldosteronism. Best Pract Res Clin Endocrinol Metab. 2020; 34(2):101417. DOI: 10.1016/j.beem.2020.101417. View

13.

Durieux V, Gevenois P . Bibliometric indicators: quality measurements of scientific publication. Radiology. 2010; 255(2):342-51. DOI: 10.1148/radiol.09090626. View

14.

Savard S, Amar L, Plouin P, Steichen O . Cardiovascular complications associated with primary aldosteronism: a controlled cross-sectional study. Hypertension. 2013; 62(2):331-6. DOI: 10.1161/HYPERTENSIONAHA.113.01060. View

15.

Grassi G, Calhoun D, Mancia G, Carey R . Resistant Hypertension Management: Comparison of the 2017 American and 2018 European High Blood Pressure Guidelines. Curr Hypertens Rep. 2019; 21(9):67. DOI: 10.1007/s11906-019-0974-3. View

16.

Eyre-Walker A, Stoletzki N . The assessment of science: the relative merits of post-publication review, the impact factor, and the number of citations. PLoS Biol. 2013; 11(10):e1001675. PMC: 3792863. DOI: 10.1371/journal.pbio.1001675. View

17.

Wang Y, Zhao N, Zhang X, Li Z, Liang Z, Yang J . Bibliometrics Analysis of Butyrophilins as Immune Regulators [1992-2019] and Implications for Cancer Prognosis. Front Immunol. 2020; 11:1187. PMC: 7338374. DOI: 10.3389/fimmu.2020.01187. View

18.

Boudry C, Baudouin C, Mouriaux F . International publication trends in dry eye disease research: A bibliometric analysis. Ocul Surf. 2017; 16(1):173-179. DOI: 10.1016/j.jtos.2017.10.002. View

19.

van Eck N, Waltman L . Citation-based clustering of publications using CitNetExplorer and VOSviewer. Scientometrics. 2017; 111(2):1053-1070. PMC: 5400793. DOI: 10.1007/s11192-017-2300-7. View

20.

Monticone S, Burrello J, Tizzani D, Bertello C, Viola A, Buffolo F . Prevalence and Clinical Manifestations of Primary Aldosteronism Encountered in Primary Care Practice. J Am Coll Cardiol. 2017; 69(14):1811-1820. DOI: 10.1016/j.jacc.2017.01.052. View