Global Trends in Polycystic Ovary Syndrome Research: A 10-year Bibliometric Analysis

Overview

Journal Front Endocrinol (Lausanne)

Specialty Endocrinology

Date 2023 Jan 26

PMID 36699019

Authors

Na Shi

Hong-Bo Ma

Affiliations

Soon will be listed here.

Abstract

Background: Polycystic ovary syndrome (PCOS) is one of the most common reproductive metabolic disorders in women, significantly affecting the biological functionalities of ovaries. This disease has garnered enormous interest from researchers. However, there is a lack of a comprehensive research concerning assessing the current status and future trends in PCOS field. This study uses bibliometric tools to comprehensively analyze the PCOS-related research progress based on the literature in the past decade.

Methods: The reported PCOS literature in the past decade is downloaded from the Web of Science database. The bibliometric software is applied to analyze the co-authorship, co-citation, and co-occurrence status.

Results: A total of 9936 publications imported into bibliometric tools for analysis show a sharp increase in the annual citations. The USA is dominant in terms of contribution in the field of PCOS, while China is making a significant contribution to the advancement of this field. Monash University is the most prolific institution with the highest H-index value. The contribution of University of Adelaide must be acknowledged. Legro RS and Teede HJ are the most active and influential authors in recent times, while Azziz R is the most contributed pioneer in this field. The Journal of is the most active journal with the highest number of publications and citations. The pathogenesis of PCOS had been a long-term forefront of research. In recent years, the health management in PCOS prevention and long-term complications was attracting more and more attention. The keywords like "gut microbiota", "microRNAs", "apoptosis", "Myo-inositol", "TNF-alpha", "androgen receptor", and "Vitamin D-deficient" are considered the latest research topics.

Conclusion: The study comprehensively analyzes the current status and global trends in the PCOS field, providing a significant reference for researchers to explore this field effectively.

Citing Articles

Research trend and hotspots of polycystic ovary syndrome with depression from 1993 to 2024: a bibliometric analysis.

Xie J, Cao Y, Wen Q, Song X, Shi Y, Gao X Front Glob Womens Health. 2024; 5:1468471.

PMID: 39669109 PMC: 11634872. DOI: 10.3389/fgwh.2024.1468471.

Investigating the metabolomic pathways in female reproductive endocrine disorders: a Mendelian randomization study.

Lu F, Wang Z, Yang Q, Yan F, Xu C, Wang M Front Endocrinol (Lausanne). 2024; 15:1438079.

PMID: 39544240 PMC: 11560792. DOI: 10.3389/fendo.2024.1438079.

Investigation of the relationship between breast cancer and clinical symptoms of polycystic ovarian syndrome: a case-control study.

Hemati A, Amini L, Haghani S, Hashemi E BMC Womens Health. 2024; 24(1):586.

PMID: 39488687 PMC: 11531183. DOI: 10.1186/s12905-024-03421-4.

Identification of necroptosis-related gene expression and the immune response in polycystic ovary syndrome.

Tang X, Ji J, Zhu L, Sun F, Wang L, Xu W J Assist Reprod Genet. 2024; 41(12):3517-3537.

PMID: 39397125 PMC: 11707095. DOI: 10.1007/s10815-024-03286-4.

Examining the Genetic Role of rs8192675 Variant in Saudi Women Diagnosed with Polycystic Ovary Syndrome.

Alsobaie S, Alageel A, Ishfaq T, Ali Khan I, Alharbi K Diagnostics (Basel). 2023; 13(20).

PMID: 37892034 PMC: 10606196. DOI: 10.3390/diagnostics13203214.

References

Chen Z, Zhao H, He L, Shi Y, Qin Y, Shi Y . Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3. Nat Genet. 2010; 43(1):55-9. DOI: 10.1038/ng.732. View

Deswal R, Dang A . Dissecting the role of micro-RNAs as a diagnostic marker for polycystic ovary syndrome: a systematic review and meta-analysis. Fertil Steril. 2020; 113(3):661-669.e2. DOI: 10.1016/j.fertnstert.2019.11.001. View

Synnestvedt M, Chen C, Holmes J . CiteSpace II: visualization and knowledge discovery in bibliographic databases. AMIA Annu Symp Proc. 2006; :724-8. PMC: 1560567. View

Legro R, Kunselman A, Dodson W, Dunaif A . Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 affected women. J Clin Endocrinol Metab. 1999; 84(1):165-9. DOI: 10.1210/jcem.84.1.5393. View

Stepto N, Cassar S, Joham A, Hutchison S, Harrison C, Goldstein R . Women with polycystic ovary syndrome have intrinsic insulin resistance on euglycaemic-hyperinsulaemic clamp. Hum Reprod. 2013; 28(3):777-84. DOI: 10.1093/humrep/des463. View

Cooper I . Bibliometrics basics. J Med Libr Assoc. 2015; 103(4):217-8. PMC: 4613387. DOI: 10.3163/1536-5050.103.4.013. View

Chen C, Dubin R, Kim M . Emerging trends and new developments in regenerative medicine: a scientometric update (2000 - 2014). Expert Opin Biol Ther. 2014; 14(9):1295-317. DOI: 10.1517/14712598.2014.920813. View

Li R, Zhang Q, Yang D, Li S, Lu S, Wu X . Prevalence of polycystic ovary syndrome in women in China: a large community-based study. Hum Reprod. 2013; 28(9):2562-9. DOI: 10.1093/humrep/det262. View

Luo Y, Cui C, Han X, Wang Q, Zhang C . The role of miRNAs in polycystic ovary syndrome with insulin resistance. J Assist Reprod Genet. 2021; 38(2):289-304. PMC: 7884539. DOI: 10.1007/s10815-020-02019-7. View

10.

Rosenfield R, Ehrmann D . The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited. Endocr Rev. 2016; 37(5):467-520. PMC: 5045492. DOI: 10.1210/er.2015-1104. View

11.

Zhang J, Sun Z, Jiang S, Bai X, Ma C, Peng Q . Probiotic V9 Regulates the Secretion of Sex Hormones in Polycystic Ovary Syndrome Patients through the Gut-Brain Axis. mSystems. 2019; 4(2). PMC: 6469956. DOI: 10.1128/mSystems.00017-19. View

12.

Teede H, Misso M, Costello M, Dokras A, Laven J, Moran L . Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Fertil Steril. 2018; 110(3):364-379. PMC: 6939856. DOI: 10.1016/j.fertnstert.2018.05.004. View

13.

Dumesic D, Oberfield S, Stener-Victorin E, Marshall J, Laven J, Legro R . Scientific Statement on the Diagnostic Criteria, Epidemiology, Pathophysiology, and Molecular Genetics of Polycystic Ovary Syndrome. Endocr Rev. 2015; 36(5):487-525. PMC: 4591526. DOI: 10.1210/er.2015-1018. View

14.

Teede H, Deeks A, Moran L . Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan. BMC Med. 2010; 8:41. PMC: 2909929. DOI: 10.1186/1741-7015-8-41. View

15.

Azziz R, Carmina E, Dewailly D, Diamanti-Kandarakis E, Escobar-Morreale H, Futterweit W . The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. Fertil Steril. 2008; 91(2):456-88. DOI: 10.1016/j.fertnstert.2008.06.035. View

16.

Shi M, Huang W, Shu L, Hou G, Guan Y, Song G . Research on polycystic ovary syndrome: a bibliometric analysis from 2009 to 2019. Gynecol Endocrinol. 2020; 37(2):121-125. DOI: 10.1080/09513590.2020.1807501. View

17.

Day F, Karaderi T, Jones M, Meun C, He C, Drong A . Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria. PLoS Genet. 2018; 14(12):e1007813. PMC: 6300389. DOI: 10.1371/journal.pgen.1007813. View

18.

Tata B, Mimouni N, Barbotin A, Malone S, Loyens A, Pigny P . Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood. Nat Med. 2018; 24(6):834-846. PMC: 6098696. DOI: 10.1038/s41591-018-0035-5. View

19.

Mu L, Sun X, Tu M, Zhang D . Non-coding RNAs in polycystic ovary syndrome: a systematic review and meta-analysis. Reprod Biol Endocrinol. 2021; 19(1):10. PMC: 7807442. DOI: 10.1186/s12958-020-00687-9. View

20.

Goodman N, Cobin R, Futterweit W, Glueck J, Legro R, Carmina E . AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS, AMERICAN COLLEGE OF ENDOCRINOLOGY, AND ANDROGEN EXCESS AND PCOS SOCIETY DISEASE STATE CLINICAL REVIEW: GUIDE TO THE BEST PRACTICES IN THE EVALUATION AND TREATMENT OF POLYCYSTIC OVARY SYNDROME - PART.... Endocr Pract. 2015; 21(12):1415-26. DOI: 10.4158/EP15748.DSCPT2. View