Treatment of Uncomplicated Gonorrhea with Single-dose Imipenem-cilastatin

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 1988 May 1

PMID 3395105

Authors

M S Verdon

F N Judson

J M Ehret

C J Root

E W Hook 3rd

W M McCormack

C A Frances

K Draft

J W Shands

H H Handsfield

Affiliations

Soon will be listed here.

Abstract

Single 500-mg intramuscular doses of imipenem-cilastatin cured 116 (95%) of 122 men and 9 of 9 women with uncomplicated gonorrhea due to beta-lactamase-negative Neisseria gonorrhoeae. Most co-existing Chlamydia trachomatis infections persisted. Imipenem-cilastatin is effective for uncomplicated gonorrhea in men but has no advantages over other available regimens.

References

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