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Intravascular Large B-cell Lymphoma Presenting with Reticular Telangiectasia on the Trunk and Panhypopituitarism: an Autopsy Case

Overview
Journal BMJ Case Rep
Specialty General Medicine
Date 2021 Mar 18
PMID 33731406
Citations 2
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Abstract

A 75-year-old woman developed redness and swelling on her truncal skin, spreading from the lower abdomen to left thigh, 2 months before being admitted to our hospital. She was urgently hospitalised because of her worsening respiratory condition. On admission, she had reticular telangiectasia, diffuse skin induration on the lower abdomen and panhypopituitarism. She was diagnosed with intravascular large B-cell lymphoma (IVLBCL) by the third random abdominal skin biopsy. After histopathological examination at autopsy, we made a final diagnosis of IVLBCL causing respiratory failure and panhypopituitarism. This is the rare case of IVLBCL-induced panhypopituitarism showing visible skin lesions.

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Case Report: Intravascular Large B-Cell Lymphoma: A Clinicopathologic Study of Four Cases With Review of Additional 331 Cases in the Literature.

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References
1.
Akhtar S, Cheesman E, Jude E . SIADH and partial hypopituitarism in a patient with intravascular large B-cell lymphoma: a rare cause of a common presentation. BMJ Case Rep. 2013; 2013. PMC: 3604444. DOI: 10.1136/bcr-2012-007147. View

2.
Lee B, Frankfort B, Eberhart C, Weinberg R . Diagnosis of intravascular lymphoma by a novel biopsy site. Ophthalmology. 2010; 118(3):586-90. PMC: 4612583. DOI: 10.1016/j.ophtha.2010.08.001. View

3.
Matsue K, Abe Y, Narita K, Kobayashi H, Kitadate A, Takeuchi M . Diagnosis of intravascular large B cell lymphoma: novel insights into clinicopathological features from 42 patients at a single institution over 20 years. Br J Haematol. 2019; 187(3):328-336. PMC: 6900202. DOI: 10.1111/bjh.16081. View

4.
Anila K, Nair R, Koshy S, Jacob P . Primary intravascular large B-cell lymphoma of pituitary. Indian J Pathol Microbiol. 2013; 55(4):549-51. DOI: 10.4103/0377-4929.107811. View

5.
Shimada K, Murase T, Matsue K, Okamoto M, Ichikawa N, Tsukamoto N . Central nervous system involvement in intravascular large B-cell lymphoma: a retrospective analysis of 109 patients. Cancer Sci. 2010; 101(6):1480-6. PMC: 11158344. DOI: 10.1111/j.1349-7006.2010.01555.x. View