Intravascular Lymphomatosis (neoplastic Angioendotheliosis) of the Central Nervous System: Case Report and Literature Review

Overview

Journal J Neurooncol

Publisher Springer

Date 1991 Oct 1

PMID 1744685

Citations 8

Authors

D Smadja

J L Mas

C Fallet-Bianco

O Meyniard

D Sicard

J De Recondo

P Rondot

Affiliations

Soon will be listed here.

Abstract

A 63-year-old woman developed gradual slowness, recurrent multifocal deficits, severe constitutional symptoms and hypopituitarism which progressed to death over 2.5 months. Elevation in lactico dehydrogenases was the main biological abnormality. Necropsy showed an intravascular malignant proliferation which proved to be a lymphoma of B-lineage. In order to better define diagnostic criteria, we reviewed previously reported cases of intravascular lymphomatosis of the central nervous system. A strategy for establishing the diagnosis is proposed.

Citing Articles

ICAM1-Negative Intravascular Large B-Cell Lymphoma of the Pituitary Gland: A Case Report and Literature Review.

Naito K, Suzuki S, Ohwada C, Ishiwata K, Ruike Y, Ishida A AACE Clin Case Rep. 2021; 7(4):249-255.

PMID: 34307847 PMC: 8282537. DOI: 10.1016/j.aace.2021.01.011.

Intravascular large B-cell lymphoma presenting with reticular telangiectasia on the trunk and panhypopituitarism: an autopsy case.

Tokushima M, Tago M, E Katsuki N, Yamashita S BMJ Case Rep. 2021; 14(3).

PMID: 33731406 PMC: 7978074. DOI: 10.1136/bcr-2020-239422.

Status epilepticus as the initial presentation of intravascular lymphoma.

Hiraga A, Ozaki D, Kamitsukasa I, Araki N, Arai K Case Rep Neurol. 2012; 4(2):107-12.

PMID: 22807906 PMC: 3398095. DOI: 10.1159/000339815.

Intravascular lymphomatosis and intracerebral haemorrhage.

Passarin M, Wen P, Vattemi E, Buffone E, Ghimenton C, Bontempini L Neurol Sci. 2010; 31(6):793-7.

PMID: 20517703 DOI: 10.1007/s10072-010-0284-7.

Intravascular lymphomatosis (IL) in a child mimicking a posterior fossa tumor.

Massimino M, Giardini R, Cefalo G, Simonetti F, Pollo B, Giombini S J Neurooncol. 2001; 51(1):47-50.

PMID: 11349880 DOI: 10.1023/a:1006476701534.

References

Madara J, Shane J, Scarlato M . Systemic endotheliomatosis: a case report. J Clin Pathol. 1975; 28(6):476-82. PMC: 475746. DOI: 10.1136/jcp.28.6.476. View

Remberger K, Gokel J, Haider M . Systemic angioendotheliomatosis of the lung. Pathol Res Pract. 1987; 182(2):265-74. DOI: 10.1016/S0344-0338(87)80116-4. View

BOTS G . Angioendotheliomatosis of the central nervous system. Acta Neuropathol. 1974; 28(1):75-8. DOI: 10.1007/BF00687520. View

Petito C, Gottlieb G, DOUGHERTY J, Petito F . Neoplastic angioendotheliosis: ultrastructural study and review of the literature. Ann Neurol. 1978; 3(5):393-9. DOI: 10.1002/ana.410030505. View

Wick M, Mills S, Scheithauer B, Cooper P, Davitz M, Parkinson K . Reassessment of malignant "angioendotheliomatosis". Evidence in favor of its reclassification as "intravascular lymphomatosis". Am J Surg Pathol. 1986; 10(2):112-23. View

Haber H, Harris-Jones J, Wells A . INTRAVASCULAR ENDOTHELIOMA (ENDOTHELIOMA IN SITU, SYSTEMIC ENDOTHELIOMATOSIS). J Clin Pathol. 1964; 17:608-11. PMC: 480842. DOI: 10.1136/jcp.17.6.608. View

Tanaka M, Yamaguchi H, Uchiyama T, Hirai S, Ishizeki J . [An autopsy case of malignant lymphoma mimicking neoplastic angioendotheliosis]. Rinsho Shinkeigaku. 1982; 22(6):507-13. View

Ansell J, Bhawan J, Cohen S, Sullivan J, Sherman D . Histiocytic lymphoma and malignant angioendotheliomatosis: one disease or two?. Cancer. 1982; 50(8):1506-12. DOI: 10.1002/1097-0142(19821015)50:8<1506::aid-cncr2820500810>3.0.co;2-3. View

SHTERN R, LIKHACHEV I . [ENDOTHELIOMATOSIS AS A SYSTEMIC TUMOR LESION]. Arkh Patol. 1963; 25:35-40. View

10.

Baxter J, Harris A, Tomkins G, Cohn M . Glucocorticoid receptors in lymphoma cells in culture: relationship to glucocorticoid killing activity. Science. 1971; 171(3967):189-91. DOI: 10.1126/science.171.3967.189. View

11.

ARNN E, Yam L, Li C . Systemic angioendotheliomatosis presenting with hemolytic anemia. Am J Clin Pathol. 1983; 80(2):246-51. DOI: 10.1093/ajcp/80.2.246. View

12.

Ansbacher L, Low N, Beck D, Boarini D, Jacoby C, Cancilla P . Neoplastic angioendotheliosis: a clinicopathological entity with multifocal presentation. Case report. J Neurosurg. 1981; 54(3):412-5. DOI: 10.3171/jns.1981.54.3.0412. View

13.

Chen P, Gaetjens E, Sher J, Somasundaram M, Lee T, How S . Malignant angioendotheliomatosis manifesting as ascending spinal cord dysfunction. N Y State J Med. 1987; 87(8):470-2. View

14.

Biller J, Challa V, Toole J, Howard V . Nonbacterial thrombotic endocarditis. A neurologic perspective of clinicopathologic correlations of 99 patients. Arch Neurol. 1982; 39(2):95-8. DOI: 10.1001/archneur.1982.00510140029007. View

15.

KERMAREC J, Canioni D, Michiels J, Kullmann B, Borg M, MARTIN P . [Malignant systemic angioendotheliomatosis. Apropos of a case with an ultrastructural and histo-immunologic study]. Ann Pathol. 1984; 4(1):61-7. View

16.

. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 39-1986. A 66-year-old woman with fever, fluctuating neurologic signs, and negative blood cultures. N Engl J Med. 1986; 315(14):874-85. DOI: 10.1056/NEJM198610023151407. View

17.

Singh A, STROBOS R, Singh B, Rothballer A, Reddy V, Puljic S . Steroid-induced remissions in CNS lymphoma. Neurology. 1982; 32(11):1267-71. DOI: 10.1212/wnl.32.11.1267. View

18.

Wrotnowski U, Mills S, Cooper P . Malignant angioendotheliomatosis. An angiotropic lymphoma?. Am J Clin Pathol. 1985; 83(2):244-8. DOI: 10.1093/ajcp/83.2.244. View

19.

Sunohara N, Mukoyama M, SATOYOSHI E . Neoplastic angioendotheliosis of the central nervous system. J Neurol. 1984; 231(1):14-9. DOI: 10.1007/BF00313646. View

20.

Fievez M, FIEVEZ C, Hustin J . Proliferating systematized angioendotheliomatosis. Arch Dermatol. 1971; 104(3):320-4. View