A Compact Multi-Distance DCS and Time Domain NIRS Hybrid System for Hemodynamic and Metabolic Measurements

Overview

Journal Sensors (Basel)

Publisher MDPI

Specialty Biotechnology

Date 2021 Feb 2

PMID 33525488

Citations 7

Authors

Caterina Amendola

Michele Lacerenza

Mauro Buttafava

Alberto Tosi

Lorenzo Spinelli

Davide Contini

Alessandro Torricelli

Affiliations

Soon will be listed here.

Abstract

In this work, we present a new multi-distance diffuse correlation spectroscopy (DCS) device integrated with a compact state-of-the-art time domain near infrared spectroscopy (TD-NIRS) device. The hybrid DCS and TD-NIRS system allows to retrieve information on blood flow, tissue oxygenation, and oxygen metabolic rate. The DCS device performances were estimated in terms of stability, repeatability, ability in retrieving variations of diffusion coefficient, influence of the tissue optical properties, effect of varying count rates and depth sensitivity. Crosstalk between DCS and TD-NIRS optical signals was also evaluated. Finally, in vivo experiments (venous and arterial cuff occlusions on the arm) were conducted to test the ability of the hybrid system in measuring blood flow variations.

Citing Articles

Fast Multi-Distance Time-Domain NIRS and DCS System for Clinical Applications.

Nabacino M, Amendola C, Contini D, Re R, Spinelli L, Torricelli A Sensors (Basel). 2024; 24(22).

PMID: 39599151 PMC: 11598675. DOI: 10.3390/s24227375.

A personalized clinical assessment: multi-sensor approach for understanding musculoskeletal health in the frail population.

Re R, Scano A, Amata O, Spinelli L, Tomba A, Brambilla C Biomed Eng Online. 2024; 23(1):91.

PMID: 39252062 PMC: 11382456. DOI: 10.1186/s12938-024-01287-z.

Assessment of power spectral density of microvascular hemodynamics in skeletal muscles at very low and low-frequency via near-infrared diffuse optical spectroscopies.

Amendola C, Buttafava M, Carteano T, Contini L, Cortese L, Durduran T Biomed Opt Express. 2023; 14(11):5994-6015.

PMID: 38021143 PMC: 10659778. DOI: 10.1364/BOE.502618.

Advanced Neuromonitoring Modalities on the Horizon: Detection and Management of Acute Brain Injury in Children.

Ko T, Catennacio E, Shin S, Stern J, Massey S, Kilbaugh T Neurocrit Care. 2023; 38(3):791-811.

PMID: 36949362 PMC: 10241718. DOI: 10.1007/s12028-023-01690-9.

A Contact-Sensitive Probe for Biomedical Optics.

Renna M, Peruch A, Sunwoo J, Starkweather Z, Martin A, Franceschini M Sensors (Basel). 2022; 22(6).

PMID: 35336531 PMC: 8953277. DOI: 10.3390/s22062361.

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