Generating Large Field of View En-face Projection Images from Intra-acquisition Motion Compensated Volumetric Optical Coherence Tomography Data

Overview

Journal Biomed Opt Express

Specialty Radiology

Date 2021 Jan 7

PMID 33408968

Citations 15

Authors

Florian Schwarzhans

Sylvia Desissaire

Stefan Steiner

Michael Pircher

Christoph K Hitzenberger

Hemma Resch

Clemens Vass

Georg Fischer

Affiliations

Soon will be listed here.

Abstract

A technique to generate large field of view projection maps of arbitrary optical coherence tomography (OCT) data is described. The technique is divided into two stages - an image acquisition stage that features a simple to use fast and robust retinal tracker to get motion free retinal OCT volume scans - and a stitching stage where OCT data from different retinal locations is first registered against a reference image using a custom pyramid-based approach and finally stitched together into one seamless large field of view (FOV) image. The method is applied to data recorded with a polarization sensitive OCT instrument in healthy subjects and glaucoma patients. The tracking and stitching accuracies are quantified, and finally, large FOV images of retinal nerve fiber layer retardation that contain the arcuate nerve fiber bundles from the optic nerve head to the raphe are demonstrated.

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