The 2021 Nucleic Acids Research Database Issue and the Online Molecular Biology Database Collection

Overview

Journal Nucleic Acids Res

Publisher Oxford University Press

Specialty Biochemistry

Date 2021 Jan 5

PMID 33396976

Citations 22

Authors

Daniel J Rigden

Xose M Fernandez

Affiliations

Soon will be listed here.

Abstract

The 2021 Nucleic Acids Research database Issue contains 189 papers spanning a wide range of biological fields and investigation. It includes 89 papers reporting on new databases and 90 covering recent changes to resources previously published in the Issue. A further ten are updates on databases most recently published elsewhere. Seven new databases focus on COVID-19 and SARS-CoV-2 and many others offer resources for studying the virus. Major returning nucleic acid databases include NONCODE, Rfam and RNAcentral. Protein family and domain databases include COG, Pfam, SMART and Panther. Protein structures are covered by RCSB PDB and dispersed proteins by PED and MobiDB. In metabolism and signalling, STRING, KEGG and WikiPathways are featured, along with returning KLIFS and new DKK and KinaseMD, all focused on kinases. IMG/M and IMG/VR update in the microbial and viral genome resources section, while human and model organism genomics resources include Flybase, Ensembl and UCSC Genome Browser. Cancer studies are covered by updates from canSAR and PINA, as well as newcomers CNCdatabase and Oncovar for cancer drivers. Plant comparative genomics is catered for by updates from Gramene and GreenPhylDB. The entire Database Issue is freely available online on the Nucleic Acids Research website (https://academic.oup.com/nar). The NAR online Molecular Biology Database Collection has been substantially updated, revisiting nearly 1000 entries, adding 90 new resources and eliminating 86 obsolete databases, bringing the current total to 1641 databases. It is available at https://www.oxfordjournals.org/nar/database/c/.

Citing Articles

PTGS2 as target of compound Huangbai liquid in the nursing of pressure ulcer.

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PMID: 39029075 PMC: 11398748. DOI: 10.1097/MD.0000000000039000.

Unveiling the role of HIST2H2AC in stroke through single-cell and transcriptome analysis.

Qin R, Huang L, Xu W, Qin Q, Liang X, Lai X Funct Integr Genomics. 2024; 24(2):76.

PMID: 38656411 DOI: 10.1007/s10142-024-01355-6.

Identification of TBK1 inhibitors against breast cancer using a computational approach supported by machine learning.

Siddiqui A, Jamal A, Zafar M, Jahan S Front Pharmacol. 2024; 15:1342392.

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Mechanism of Sophorae Flavescentis Radix against ovarian cancer via new pharmacology, molecular docking, and experimental verification.

Fu X, Liang F Naunyn Schmiedebergs Arch Pharmacol. 2024; 397(9):6837-6850.

PMID: 38561549 DOI: 10.1007/s00210-024-03065-z.

Exosome lncRNA IFNG-AS1 derived from mesenchymal stem cells of human adipose ameliorates neurogenesis and ASD-like behavior in BTBR mice.

Fu Y, Zhang Y, Liu R, Xu M, Xie J, Zhang X J Nanobiotechnology. 2024; 22(1):66.

PMID: 38368393 PMC: 10874555. DOI: 10.1186/s12951-024-02338-2.

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