Signatures of Selection in Composite Vrindavani Cattle of India

Overview

Journal Front Genet

Date 2021 Jan 4

PMID 33391343

Citations 18

Authors

Akansha Singh

Arnav Mehrotra

Cedric Gondro

Andrea Renata da Silva Romero

Ashwni Kumar Pandey

A Karthikeyan

Aamir Bashir

B P Mishra

Triveni Dutt

Amit Kumar

Affiliations

Soon will be listed here.

Abstract

Vrindavani is an Indian composite cattle breed developed by crossbreeding taurine dairy breeds with native indicine cattle. The constituent breeds were selected for higher milk production and adaptation to the tropical climate. However, the selection response for production and adaptation traits in the Vrindavani genome is not explored. In this study, we provide the first overview of the selection signatures in the Vrindavani genome. A total of 96 Vrindavani cattle were genotyped using the BovineSNP50 BeadChip and the SNP genotype data of its constituent breeds were collected from a public database. Within-breed selection signatures in Vrindavani were investigated using the integrated haplotype score (iHS). The Vrindavani breed was also compared to each of its parental breeds to discover between-population signatures of selection using two approaches, cross-population extended haplotype homozygosity (XP-EHH) and fixation index ( ). We identified 11 common regions detected by more than one method harboring genes such as associated with production and adaptation. Overall, our results suggested stronger selective pressure on regions responsible for adaptation compared to milk yield.

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