A Curated Database Reveals Trends in Single-cell Transcriptomics

Overview

Journal Database (Oxford)

Specialty Biology

Date 2020 Nov 28

PMID 33247933

Citations 94

Authors

Valentine Svensson

Eduardo da Veiga Beltrame

Lior Pachter

Affiliations

Soon will be listed here.

Abstract

The more than 1000 single-cell transcriptomics studies that have been published to date constitute a valuable and vast resource for biological discovery. While various 'atlas' projects have collated some of the associated datasets, most questions related to specific tissue types, species or other attributes of studies require identifying papers through manual and challenging literature search. To facilitate discovery with published single-cell transcriptomics data, we have assembled a near exhaustive, manually curated database of single-cell transcriptomics studies with key information: descriptions of the type of data and technologies used, along with descriptors of the biological systems studied. Additionally, the database contains summarized information about analysis in the papers, allowing for analysis of trends in the field. As an example, we show that the number of cell types identified in scRNA-seq studies is proportional to the number of cells analysed. Database URL: www.nxn.se/single-cell-studies/gui.

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