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Impact of Nonlordotic Sagittal Alignment on Short-term Outcomes of Cervical Disc Replacement

Overview
Journal Neurospine
Date 2020 Oct 6
PMID 33022164
Citations 5
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Abstract

Objective: To evaluate outcomes of cervical disc replacement (CDR) in patients with nonlordotic alignment.

Methods: Patients who underwent CDR were retrospectively reviewed and divided into 3 cohorts: (1) neutral/lordotic segmental and C2-7 Cobb angle (L), (2) nonlordotic segmental Cobb angle, lordotic C2-7 Cobb angle (NL-S), and (3) nonlordotic segmental and C2-7 Cobb angle (NL-SC). Radiographic and patient-reported outcomes (PROMs) were compared.

Results: One-hundred five patients were included (L: 37, NL-S: 30, NL-SC: 38). A significant gain in segmental lordosis was seen in all cohorts at < 6 months (L: -1.90° [p = 0.007]; NL-S: -5.16° [p < 0.0001]; NL-SC: -6.00° [p < 0.0001]) and ≥ 6 months (L: -2.07° [p = 0.031; NL-S: -6.04° [p < 0.0001]; NL-SC: -6.74° [p < 0.0001]), with greater lordosis generated in preoperatively nonlordotic cohorts (p < 0.0001). C2-7 lordosis improved in the preoperatively nonlordotic cohort (NL-SC: 8.04°) at follow-up of < 6 months (-4.15°, p = 0.003) and ≥ 6 months (-6.40°, p = 0.003), but not enough to create lordotic alignment (< 6 months: 3.89°; ≥ 6 months: 4.06°). All cohorts showed improvement in Neck Disability Index, visual analogue scale (VAS) neck, and VAS arm, without significant difference among groups in the amount of improvement ( ≥ 6-month PROMs follow-up = 69%).

Conclusion: In patients without major kyphotic deformity, CDR has the potential to generate and maintain lordosis and improve PROMs in the short-term, and can be an effective treatment option for patients with nonlordotic alignment.

Citing Articles

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Lee J, Lee Y, Chang M, Lee J Neurospine. 2023; 20(3):1047-1060.

PMID: 37798997 PMC: 10562247. DOI: 10.14245/ns.2346498.249.


Cervical sagittal balance after consecutive three-level hybrid surgery versus anterior cervical discectomy and fusion: radiological results from a single-center experience.

Chen S, Deng Y, Liu H, Wu T, Huang K, He J J Orthop Surg Res. 2023; 18(1):345.

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Cervical kinematic change after posterior full-endoscopic cervical foraminotomy for disc herniation or foraminal stenosis.

Paik S, Choi Y, Chung C, Won Y, Park S, Yang S PLoS One. 2023; 18(2):e0281926.

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Association of Craniocervical Sagittal Alignment With the Outcomes of Cervical Disc Replacement.

Shen Y, Yang Y, Hong Y, Ding C, Rong X, Meng Y Global Spine J. 2022; 14(3):846-855.

PMID: 36044545 PMC: 11192106. DOI: 10.1177/21925682221124531.


Commentary on "Impact of Nonlordotic Sagittal Alignment on Short-term Outcomes of Cervical Disc Replacement".

Zhang K, Liu H, Wu T Neurospine. 2021; 18(2):413-414.

PMID: 34218625 PMC: 8255763. DOI: 10.14245/ns.2142442.221.

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