Recent Advances in Use of Fresh Frozen Plasma, Cryoprecipitate, Immunoglobulins, and Clotting Factors for Transfusion Support in Patients with Hematologic Disease

Overview

Journal Semin Hematol

Specialty Hematology

Date 2020 Sep 7

PMID 32892846

Citations 10

Authors

Prajeeda M Nair

Matthew J Rendo

Kristin M Reddoch-Cardenas

Jason K Burris

Michael A Meledeo

Andrew P Cap

Affiliations

Soon will be listed here.

Abstract

Hematologic diseases include a broad range of acquired and congenital disorders, many of which affect plasma proteins that control hemostasis and immune responses. Therapeutic interventions for these disorders include transfusion of plasma, cryoprecipitate, immunoglobulins, or convalescent plasma-containing therapeutic antibodies from patients recovering from infectious diseases, as well as concentrated pro- or anticoagulant factors. This review will focus on recent advances in the uses of plasma and its derivatives for patients with acquired and congenital hematologic disorders.

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