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Michael A Meledeo

Explore the profile of Michael A Meledeo including associated specialties, affiliations and a list of published articles. Areas
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Citations 80
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Recent Articles
1.
Schauer S, Conte J, Hudson I, Mendez J, Sifuentes D, Mancha F, et al.
Transfusion . 2025 Feb; PMID: 40021807
Introduction: Hemorrhage is the leading cause of death after trauma. Blood transfusions are used to restore physiology but are stored in citrate preservative which can bind electrolytes, particularly calcium, leading...
2.
Reddoch-Cardenas K, Meledeo M
Blood . 2024 May; 143(20):2019-2020. PMID: 38753356
No abstract available.
3.
Greene N, McIntosh C, Meledeo M, Reddoch-Cardenas K
Mil Med . 2024 May; 189(Supplement_3):560-567. PMID: 38739474
Introduction: The United States Army has shifted doctrine to focus on large-scale combat operations against peer to near-peer adversaries. Future conflicts could result in a limited supply chain, leaving medical...
4.
Reddoch-Cardenas K, Perez S, Ferdin J, Meledeo M
Transfusion . 2024 Mar; 64 Suppl 2:S146-S154. PMID: 38491915
Background: Platelet concentrates (PCs) used for transfusion can be produced by apheresis or derived from whole blood (WB). The Reveos device is the first US Food and Drug Administration-approved automated...
5.
Wu X, Cap A, Bynum J, Chance T, Darlington D, Meledeo M
Sci Rep . 2024 Feb; 14(1):3874. PMID: 38365865
Pre-hospital potentially preventable trauma related deaths are mainly due to hypoperfusion-induced tissue hypoxia leading to irreversible organ dysfunction at or near the point of injury or during transportation prior to...
6.
Yazer M, Werneiwski K, Thompson P, Titlestad K, Watkins T, Smith S, et al.
Transfusion . 2024 Jan; 64 Suppl 2:S27-S33. PMID: 38251751
Background: Whole blood (WB) collections can occur downrange for immediate administration. An important aspect of these collections is determining when the unit is sufficiently full. This project tested a novel...
7.
Leung J, Strong C, Badior K, Robertson M, Wu X, Meledeo M, et al.
Sci Adv . 2023 Dec; 9(48):eadi0508. PMID: 38039367
Platelet transfusions are essential for managing bleeding and hemostatic dysfunction and could be expanded as a cell therapy due to the multifunctional role of platelets in various diseases. Creating these...
8.
Edwards T, Meledeo M, Peltier G, Henderson A, Pompa L, Bynum J
J Vet Emerg Crit Care (San Antonio) . 2023 Nov; 34(1):63-68. PMID: 37966879
Objective: To determine the characteristics of canine freeze-dried plasma (cFDP) as it is serially diluted with sterile water. Design: In vitro experimental study. Setting: Government blood and coagulation research laboratory....
9.
Peltier G, Meledeo M
J Trauma Acute Care Surg . 2023 May; 95(2S Suppl 1):S152-S156. PMID: 37246299
Background: Unmanned aerial vehicles (UAVs) have been shown to shorten delivery times of medical products in health care, providing a potential answer to the question of prehospital resuscitation where blood...
10.
Knight C, Bebarta V, Meledeo M, Ross E, Wu X, Bynum J, et al.
Transfusion . 2023 Mar; 63 Suppl 3:S256-S262. PMID: 36965171
Background: Hemorrhagic shock remains a leading cause of death in both military and civilian trauma casualties. While standard of care involves blood product administration, maintaining normothermia, and restoring hemostatic function,...