Diffusion Tensor Imaging Study of Brain Precentral Gyrus and Postcentral Gyrus During Normal Brain Aging Process

Overview

Journal Brain Behav

Specialty Psychology

Date 2020 Aug 27

PMID 32844600

Citations 12

Authors

Ling Zhou

Na Tian

Zuo-Jun Geng

Bing-Kun Wu

Li-Ying Dong

Mei-Rong Wang

Affiliations

Soon will be listed here.

Abstract

Objective: To study the changes of white matter tracts in precentral gyrus and postcentral gyrus during normal brain aging process by analyzing fractional anisotropy (FA) values obtained from diffusion tensor imaging (DTI) technology.

Methods: Magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) were conducted on 120 healthy right-handed subjects. The subjects were separated into four age groups, namely Young Male/Female (<45 years old) and Senior Male/Female (>45 years old). Each subject undertakes routine MRI and DTI scans. Left/right precentral and left/right postcentral gyrus are automatically detected on the image. The area for region of interest (ROI) is set to be 18 ± 2 mm .

Results: For each age group, the FA values of white matter in precentral gyrus and postcentral gyrus are statistically different (p < .05) in both left and right sides of the brain across different age groups and genders. Additionally, the FA values are statistically different (p < .05) between two young and senior age groups across different genders, brain regions, and hemispheres.

Conclusion: The FA values of precentral gyrus and postcentral gyrus are statistically different across genders, age groups, and hemispheres. Additionally, the FA values of both precentral gyrus and postcentral gyrus decrease over time, which is a strong indication of aging.

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