Retest positive for SARS-CoV-2 RNA of "recovered" Patients with COVID-19: Persistence, Sampling Issues, or Re-infection?

Overview

Journal J Med Virol

Specialty Microbiology

Date 2020 Jun 4

PMID 32492212

Citations 72

Authors

Hanyujie Kang

Yishan Wang

Zhaohui Tong

Xuefeng Liu

Affiliations

Soon will be listed here.

Abstract

"Retest Positive" for severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) from "recovered" coronavirus disease-19 (COVID-19) has been reported and raised several important questions for this novel coronavirus and COVID-19 disease. In this commentary, we discussed several questions: (a) Can SARS-CoV-2 re-infect the individuals who recovered from COVID-19? This question is also associated with other questions: whether or not SARS-CoV-2 infection induces protective reaction or neutralized antibody? Will SARS-CoV-2 vaccines work? (b) Why could some recovered patients with COVID-19 be re-tested positive for SARS-CoV-2 RNA? (c) Are some recovered pwith atients COVID-19 with re-testing positive for SARS-CoV-2 RNA infectious? and (d) How should the COVID-19 patients with retest positive for SARS-CoV-2 be managed?

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