Bruch's Membrane Opening Minimum Rim Width in the Differential Diagnosis of Optic Neuropathies

Overview

Journal Neuroophthalmology

Specialty Neurology

Date 2020 May 13

PMID 32395154

Citations 2

Authors

Joana Braga

Ricardo Soares

Monica Loureiro

Ligia Ribeiro

Dalia Meira

Affiliations

Soon will be listed here.

Abstract

Observing optic disc pallor during a patient's first visit frequently raises a diagnostic challenge, particularly in regards to whether the cause is due to glaucoma or another form of optic neuropathy. Bruch's membrane opening (BMO) was recently discovered as the anatomical border of the optic disc. BMO minimum rim width (BMO-MRW) seems to be a reliable representation of the neuroretinal rim. In our study, we demonstrate the ability of BMO-MRWs to differentiate between glaucomatous and non-glaucomatous. Additionally, we propose an MRW ratio which may allow discrimination of open angle glaucoma from either non-arteritic anterior ischaemic optic neuropathy or compressive optic neuropathy.

Citing Articles

Non-arteritic anterior ischemic and glaucomatous optic neuropathy: Implications for neuroretinal rim remodeling with disease severity.

Eadie B, Dyachok O, Quach J, Maxner C, Rafuse P, Shuba L PLoS One. 2023; 18(5):e0286007.

PMID: 37200340 PMC: 10194940. DOI: 10.1371/journal.pone.0286007.

Automated macular segmentation can distinguish glaucomatous from compressive optic neuropathy.

Machado Soares R, Braga J, Fernandes J, Cunha Ferreira C, Ribeiro L, Alves H Graefes Arch Clin Exp Ophthalmol. 2023; 261(6):1701-1712.

PMID: 36625929 PMC: 10198839. DOI: 10.1007/s00417-022-05962-6.

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