Ecology, Structure, and Evolution of Phages

Overview

Journal Annu Rev Virol

Publisher Annual Reviews

Specialty Microbiology

Date 2020 May 12

PMID 32392456

Citations 9

Authors

Sundharraman Subramanian

Kristin N Parent

Sarah M Doore

Affiliations

Soon will be listed here.

Abstract

Numerous bacteriophages-viruses of bacteria, also known as phages-have been described for hundreds of bacterial species. The Gram-negative species are close relatives of , yet relatively few previously described phages appear to exclusively infect this genus. Recent efforts to isolate phages have indicated these viruses are surprisingly abundant in the environment and have distinct genomic and structural properties. In addition, at least one model system used for experimental evolution studies has revealed a unique mechanism for developing faster infection cycles. Differences between these bacteriophages and other well-described model systems may mirror differences between their hosts' ecology and defense mechanisms. In this review, we discuss the history of phages and recent developments in their isolation and characterization and the structural information available for three model systems, Sf6, Sf14, and HRP29; we also provide an overview of potential selective pressures guiding both phage and host evolution.

Citing Articles

Moo19 and B2: Structures of podophages with = 9 geometry and tailspikes with esterase activity.

Subramanian S, Bergland Drarvik S, Tinney K, Doore S, Parent K Sci Adv. 2024; 10(51):eadt0022.

PMID: 39693418 PMC: 11654681. DOI: 10.1126/sciadv.adt0022.

The phage fought the cells, and the phage won: a satellite symposium at the ASV 2023 annual meeting.

Parent K J Virol. 2023; 97(12):e0142023.

PMID: 37991366 PMC: 10734453. DOI: 10.1128/jvi.01420-23.

Cryo-EM structure of a Shigella podophage reveals a hybrid tail and novel decoration proteins.

Subramanian S, Bergland Drarvik S, Tinney K, Parent K Structure. 2023; 32(1):24-34.e4.

PMID: 37909043 PMC: 10842012. DOI: 10.1016/j.str.2023.10.007.

The Outer Membrane Cytochrome OmcA Is Essential for Infection of Shewanella oneidensis by a Zebrafish-Associated Bacteriophage.

Grenfell A, Intile P, McFarlane J, Leung D, Abdalla K, Wold M J Bacteriol. 2023; 205(6):e0046922.

PMID: 37227287 PMC: 10294696. DOI: 10.1128/jb.00469-22.

Design of a Bacteriophage Cocktail Active against Species and Testing of Its Therapeutic Potential in .

Filippov A, Su W, Sergueev K, Kevorkian R, Snesrud E, Srijan A Antibiotics (Basel). 2022; 11(11).

PMID: 36421303 PMC: 9686686. DOI: 10.3390/antibiotics11111659.

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