Bacterial Flagellar Motor PL-ring Disassembly Subcomplexes Are Widespread and Ancient

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 2020 Apr 4

PMID 32241888

Citations 16

Authors

Mohammed Kaplan

Michael J Sweredoski

Joao P G L M Rodrigues

Elitza I Tocheva

Yi-Wei Chang

Davi R Ortega

Morgan Beeby

Grant J Jensen

Affiliations

Soon will be listed here.

Abstract

The bacterial flagellum is an amazing nanomachine. Understanding how such complex structures arose is crucial to our understanding of cellular evolution. We and others recently reported that in several Gammaproteobacterial species, a relic subcomplex comprising the decorated P and L rings persists in the outer membrane after flagellum disassembly. Imaging nine additional species with cryo-electron tomography, here, we show that this subcomplex persists after flagellum disassembly in other phyla as well. Bioinformatic analyses fail to show evidence of any recent horizontal transfers of the P- and L-ring genes, suggesting that this subcomplex and its persistence is an ancient and conserved feature of the flagellar motor. We hypothesize that one function of the P and L rings is to seal the outer membrane after motor disassembly.

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