Functional and Biochemical Features of Alcohol Dehydrogenase in Four Species of the Obscura Group of Drosophila

Overview

Journal Genetica

Specialties Cell Biology
Genetics

Date 1988 Jul 31

PMID 3209073

Citations 3

Authors

J J Hernandez

L Vilageliu

R Gonzalez-Duarte

Affiliations

Soon will be listed here.

Abstract

The biochemical features of ADH of four Drosophila species of the obscura group have been studied. The relationship between ethanol tolerance and ADH activity has been investigated. Propan-2-ol and acetone concentrations have been determined in propan-2-ol treated flies and ADH activity has been followed during 96 h of propan-2-ol treatment. Data on the ADH system confirm constructed phylogenies based on electrophoretic variation and chromosome homologies.

Citing Articles

The Adh genomic region of Drosophila ambigua: evolutionary trends in different species.

Marfany G, Gonzalez-Duarte R J Mol Evol. 1991; 32(6):454-62.

PMID: 1908016 DOI: 10.1007/BF02102647.

The Adh in Drosophila: chromosomal location and restriction analysis in species with different phylogenetic relationships.

Visa N, Marfany G, Vilageliu L, Albalat R, Atrian S, Gonzalez-Duarte R Chromosoma. 1991; 100(5):315-22.

PMID: 1860376 DOI: 10.1007/BF00360530.

Evidence for retrotranscription of protein-coding genes in the Drosophila subobscura genome.

Marfany G, Gonzalez-Duarte R J Mol Evol. 1992; 35(6):492-501.

PMID: 1474603 DOI: 10.1007/BF00160210.

References

Jacobson K, Murphy J, Knopp J, Ortiz J . Multiple forms of drosophila alcohol dehydrogenase. 3. Conversion of one form to another by nicotinamide adenine dinucleotide or acetone. Arch Biochem Biophys. 1972; 149(1):22-35. DOI: 10.1016/0003-9861(72)90295-0. View

Cabrera V, Gonzalez A, Larruga J, Gullon A . GENETIC DISTANCE AND EVOLUTIONARY RELATIONSHIPS IN THE DROSOPHILA OBSCURA GROUP. Evolution. 2017; 37(4):675-689. DOI: 10.1111/j.1558-5646.1983.tb05589.x. View

Juan E, Gonzalez-Duarte R . Determination of some biochemical and structural features of alcohol dehydrogenases from Drosophila simulans and Drosophila virilis. Comparison of their properties with the Drosophila melanogaster Adhs enzyme. Biochem J. 1981; 195(1):61-9. PMC: 1162855. DOI: 10.1042/bj1950061. View

Kamping A, van Delden W . Alcohol dehydrogenase polymorphism in populations of Drosophila melanogaster. II. Relation between ADH activity and adult mortality. Biochem Genet. 1978; 16(5-6):541-51. DOI: 10.1007/BF00484218. View

Gonzalez-Duarte R, Vilageliu L . Metabolic response to ethanol and isopropanol in D. funebris and D. immigrans. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1985; 80(1):189-93. DOI: 10.1016/0742-8413(85)90153-7. View

Geer B, McKechnie S, Langevin M . The effect of dietary ethanol on the composition of lipids of Drosophila melanogaster larvae. Biochem Genet. 1986; 24(1-2):51-69. DOI: 10.1007/BF00502978. View

Savakis C, Ashburner M . A simple gene with a complex pattern of transcription: the alcohol dehydrogenase gene of Drosophila melanogaster. Cold Spring Harb Symp Quant Biol. 1985; 50:505-14. DOI: 10.1101/sqb.1985.050.01.062. View

Winberg J, Hovik R, Juan E, Gonzalez-Duarte R . Biochemical properties of alcohol dehydrogenase from Drosophila lebanonensis. Biochem J. 1986; 235(2):481-90. PMC: 1146711. DOI: 10.1042/bj2350481. View

Kreitman M . Nucleotide polymorphism at the alcohol dehydrogenase locus of Drosophila melanogaster. Nature. 1983; 304(5925):412-7. DOI: 10.1038/304412a0. View

10.

Daly K, Clarke B . Selection associated with the alcohol dehydrogenase locus in Drosophila melanogaster: differential survival of adults maintained on low concentrations of ethanol. Heredity (Edinb). 1981; 46(Pt 2):219-26. DOI: 10.1038/hdy.1981.29. View

11.

Fletcher T, Ayala F, Thatcher D, Chambers G . Structural analysis of the ADHS electromorph of Drosophila melanogaster. Proc Natl Acad Sci U S A. 1978; 75(11):5609-12. PMC: 393016. DOI: 10.1073/pnas.75.11.5609. View

12.

McDonald J, Avise J . Evidence for the adaptive significance of enzyme activity levels: interspecific variation in alpha-GPDH and ADH in Drosophila. Biochem Genet. 1976; 14(3-4):347-55. DOI: 10.1007/BF00484773. View

13.

Ursprung H, Leone J . Alcohol dehydrogenases: a polymorphism in Drosophila melanogaster. J Exp Zool. 1965; 160(2):147-54. DOI: 10.1002/jez.1401600202. View

14.

Heberlein U, England B, Tjian R . Characterization of Drosophila transcription factors that activate the tandem promoters of the alcohol dehydrogenase gene. Cell. 1985; 41(3):965-77. DOI: 10.1016/s0092-8674(85)80077-5. View

15.

Atrian S, Gonzalez-Duarte R . Purification and molecular characterization of alcohol dehydrogenase from Drosophila hydei: conservation in the biochemical features of the enzyme in several species of Drosophila. Biochem Genet. 1985; 23(11-12):891-911. DOI: 10.1007/BF00499936. View

16.

Vilageliu L, Gonzalez-Duarte R . Alcohol dehydrogenase from Drosophila funebris and Drosophila immigrans: molecular and evolutionary aspects. Biochem Genet. 1984; 22(9-10):797-815. DOI: 10.1007/BF00499474. View

17.

McKenzie J, Parsons P . Microdifferentiation in a natural population of Drosophila melanogaster to alcohol in the environment. Genetics. 1974; 77(2):385-94. PMC: 1213135. DOI: 10.1093/genetics/77.2.385. View

18.

Juan E, Gonzalez-Duarte R . Purification and enzyme stability of alcohol dehydrogenase from Drosophila simulans, Drosophila virilis and Drosophila melanogaster adhS. Biochem J. 1980; 189(1):105-10. PMC: 1161922. DOI: 10.1042/bj1890105. View

19.

Thatcher D . The complete amino acid sequence of three alcohol dehydrogenase alleloenzymes (AdhN-11, AdhS and AdhUF) from the fruitfly Drosophila melanogaster. Biochem J. 1980; 187(3):875-83. PMC: 1162474. DOI: 10.1042/bj1870875. View

20.

Schwartz M, ODonnell J, Sofer W . Origin of the multiple forms of alcohol dehydrogenase from Drosophila melanogaster. Arch Biochem Biophys. 1979; 194(2):365-78. DOI: 10.1016/0003-9861(79)90629-5. View