Application of Non-invasive Imaging in Inflammatory Disease Conditions to Evaluate Subclinical Coronary Artery Disease

Overview

Journal Curr Rheumatol Rep

Publisher Current Science

Specialty Rheumatology

Date 2019 Dec 14

PMID 31832865

Citations 3

Authors

Harry Choi

Domingo E Uceda

Amit K Dey

Nehal N Mehta

Affiliations

Soon will be listed here.

Abstract

Purpose Of Review: Traditional risk models, such as the Framingham risk score, fail to capture the increased cardiovascular disease risk seen in patients with chronic inflammatory diseases. This review will cover imaging modalities and their emerging applications in assessing subclinical cardiovascular disease for both research and clinical care in patients with chronic inflammatory diseases.

Recent Findings: Multiple imaging modalities have been studied to assess for subclinical cardiovascular disease via functional/physiologic, inflammatory, and anatomic assessment in patients with chronic inflammatory diseases. The use of imaging to evaluate subclinical cardiovascular disease in patients with chronic inflammatory diseases has the potential to capture early sub-clinical atherosclerosis, to improve risk stratification of future cardiovascular events, and to guide effective disease management.

Citing Articles

Endothelial dysfunction and increased carotid intima-media thickness in patients with spondyloarthritis without traditional cardiovascular risk factors.

Ben Tekaya A, Boukriba S, Fendri A, Rouached L, Saidane O, Bouden S RMD Open. 2022; 8(2).

PMID: 35793876 PMC: 9260841. DOI: 10.1136/rmdopen-2022-002270.

Increased epicardial adipose tissue thickness correlates with endothelial dysfunction in spondyloarthritis.

Ben Tekaya A, Mehmli T, Ben Mrad I, Fendri A, Boukriba S, Bouden S Clin Rheumatol. 2022; 41(10):3017-3025.

PMID: 35776282 DOI: 10.1007/s10067-022-06261-5.

Role of Periodontal Infection, Inflammation and Immunity in Atherosclerosis.

Choi H, Dey A, Priyamvara A, Aksentijevich M, Bandyopadhyay D, Dey D Curr Probl Cardiol. 2020; 46(3):100638.

PMID: 32646544 PMC: 8761259. DOI: 10.1016/j.cpcardiol.2020.100638.

References

Skeoch S, Cristinacce P, Williams H, Pemberton P, Xu D, Sun J . Imaging atherosclerosis in rheumatoid arthritis: evidence for increased prevalence, altered phenotype and a link between systemic and localised plaque inflammation. Sci Rep. 2017; 7(1):827. PMC: 5429790. DOI: 10.1038/s41598-017-00989-w. View

Fischer C, Hulten E, Belur P, Smith R, Voros S, Villines T . Coronary CT angiography versus intravascular ultrasound for estimation of coronary stenosis and atherosclerotic plaque burden: a meta-analysis. J Cardiovasc Comput Tomogr. 2013; 7(4):256-66. DOI: 10.1016/j.jcct.2013.08.006. View

Goff Jr D, Lloyd-Jones D, Bennett G, Coady S, DAgostino R, Gibbons R . 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2013; 129(25 Suppl 2):S49-73. DOI: 10.1161/01.cir.0000437741.48606.98. View

Joannides R, Haefeli W, Linder L, Richard V, Bakkali E, Thuillez C . Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo. Circulation. 1995; 91(5):1314-9. DOI: 10.1161/01.cir.91.5.1314. View

Lorenz M, Polak J, Kavousi M, Mathiesen E, Volzke H, Tuomainen T . Carotid intima-media thickness progression to predict cardiovascular events in the general population (the PROG-IMT collaborative project): a meta-analysis of individual participant data. Lancet. 2012; 379(9831):2053-62. PMC: 3918517. DOI: 10.1016/S0140-6736(12)60441-3. View

Laurent S, Boutouyrie P, Asmar R, Gautier I, Laloux B, Guize L . Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension. 2001; 37(5):1236-41. DOI: 10.1161/01.hyp.37.5.1236. View

Sandoo A, Veldhuijzen van Zanten J, Metsios G, Carroll D, Kitas G . Vascular function and morphology in rheumatoid arthritis: a systematic review. Rheumatology (Oxford). 2011; 50(11):2125-39. DOI: 10.1093/rheumatology/ker275. View

Taverner D, Paredes S, Ferre R, Masana L, Castro A, Vallve J . Assessment of arterial stiffness variables in patients with rheumatoid arthritis: A mediation analysis. Sci Rep. 2019; 9(1):4543. PMC: 6418197. DOI: 10.1038/s41598-019-41069-5. View

Bodnar N, Kerekes G, Seres I, Paragh G, Kappelmayer J, Nemethne Z . Assessment of subclinical vascular disease associated with ankylosing spondylitis. J Rheumatol. 2011; 38(4):723-9. DOI: 10.3899/jrheum.100668. View

10.

Zieman S, Melenovsky V, Kass D . Mechanisms, pathophysiology, and therapy of arterial stiffness. Arterioscler Thromb Vasc Biol. 2005; 25(5):932-43. DOI: 10.1161/01.ATV.0000160548.78317.29. View

11.

Batty J, Subba S, Luke P, Gigi L, Sinclair H, Kunadian V . Intracoronary Imaging in the Detection of Vulnerable Plaques. Curr Cardiol Rep. 2016; 18(3):28. PMC: 4754333. DOI: 10.1007/s11886-016-0705-1. View

12.

den Ruijter H, Peters S, Anderson T, Britton A, Dekker J, Eijkemans M . Common carotid intima-media thickness measurements in cardiovascular risk prediction: a meta-analysis. JAMA. 2012; 308(8):796-803. DOI: 10.1001/jama.2012.9630. View

13.

Nasir K, Bittencourt M, Blaha M, Blankstein R, Agatson A, Rivera J . Implications of Coronary Artery Calcium Testing Among Statin Candidates According to American College of Cardiology/American Heart Association Cholesterol Management Guidelines: MESA (Multi-Ethnic Study of Atherosclerosis). J Am Coll Cardiol. 2015; 66(15):1657-68. DOI: 10.1016/j.jacc.2015.07.066. View

14.

Ogawa M, Nakamura S, Saito Y, Kosugi M, Magata Y . What can be seen by 18F-FDG PET in atherosclerosis imaging? The effect of foam cell formation on 18F-FDG uptake to macrophages in vitro. J Nucl Med. 2011; 53(1):55-8. DOI: 10.2967/jnumed.111.092866. View

15.

Kiss E, Soltesz P, Der H, Kocsis Z, Tarr T, Bhattoa H . Reduced flow-mediated vasodilation as a marker for cardiovascular complications in lupus patients. J Autoimmun. 2006; 27(4):211-7. DOI: 10.1016/j.jaut.2006.09.008. View

16.

Papadopoulou S, Neefjes L, Schaap M, Li H, Capuano E, van der Giessen A . Detection and quantification of coronary atherosclerotic plaque by 64-slice multidetector CT: a systematic head-to-head comparison with intravascular ultrasound. Atherosclerosis. 2011; 219(1):163-70. DOI: 10.1016/j.atherosclerosis.2011.07.005. View

17.

Zeller C, Appenzeller S . Cardiovascular disease in systemic lupus erythematosus: the role of traditional and lupus related risk factors. Curr Cardiol Rev. 2009; 4(2):116-22. PMC: 2779351. DOI: 10.2174/157340308784245775. View

18.

Kolossvary M, Karady J, Kikuchi Y, Ivanov A, Schlett C, Lu M . Radiomics versus Visual and Histogram-based Assessment to Identify Atheromatous Lesions at Coronary CT Angiography: An ex Vivo Study. Radiology. 2019; 293(1):89-96. PMC: 6776230. DOI: 10.1148/radiol.2019190407. View

19.

Giles J, Szklo M, Post W, Petri M, Blumenthal R, Lam G . Coronary arterial calcification in rheumatoid arthritis: comparison with the Multi-Ethnic Study of Atherosclerosis. Arthritis Res Ther. 2009; 11(2):R36. PMC: 2688181. DOI: 10.1186/ar2641. View

20.

Willerson J, Ridker P . Inflammation as a cardiovascular risk factor. Circulation. 2004; 109(21 Suppl 1):II2-10. DOI: 10.1161/01.CIR.0000129535.04194.38. View