Effects of Lycium Barbarum Polysaccharides on Health and Aging of Depend on

Overview

Journal Oxid Med Cell Longev

Publisher Wiley

Specialties Cell Biology
Endocrinology

Date 2019 Oct 5

PMID 31583041

Citations 18

Authors

Zhaokang Zhang

Yannan Zhou

Haitao Fan

Kirunda John Billy

Yunjie Zhao

Xuan Zhan

Lijian Yang

Ya Jia

Affiliations

Soon will be listed here.

Abstract

As the global population ages, searching for drugs and functional foods which can slow down the aging process has attracted a number of researchers. In this paper, the Lycium barbarum polysaccharides (LBP) extracted from Lycium barbarum was characterized and the effects of LBP on the aging and health of were studied. Results showed that LBP can prolong the lifespan, improve the abilities to withstand environmental stress, enhance reproductive potentials, and maintain muscle integrity of . By using genetically mutated strains, RNAi gene silencing, and measuring the mRNA expression level, it was demonstrated that the lifespan of was extended by LBP mainly through , , and . The present study might provide a basis for further study of LBP as a food or drug to interfere with aging and reduce the incidence of age-related diseases.

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