Identification of Neurological Disease Targets of Natural Products by Computational Screening

Overview

Journal Neural Regen Res

Date 2019 Aug 10

PMID 31397338

Citations 3

Authors

Janez Konc

Affiliations

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References

Baran P . Natural Product Total Synthesis: As Exciting as Ever and Here To Stay. J Am Chem Soc. 2018; 140(14):4751-4755. DOI: 10.1021/jacs.8b02266. View

Konc J . Binding site comparisons for target-centered drug discovery. Expert Opin Drug Discov. 2019; 14(5):445-454. DOI: 10.1080/17460441.2019.1588883. View

Abdulla A, Zhao X, Yang F . Natural Polyphenols Inhibit Lysine-Specific Demethylase-1 . J Biochem Pharmacol Res. 2013; 1(1):56-63. PMC: 3646376. View

Kores K, Lesnik S, Bren U, Janezic D, Konc J . Discovery of Novel Potential Human Targets of Resveratrol by Inverse Molecular Docking. J Chem Inf Model. 2019; 59(5):2467-2478. DOI: 10.1021/acs.jcim.8b00981. View

Abusnina A, Keravis T, Zhou Q, Justiniano H, Lobstein A, Lugnier C . Tumour growth inhibition and anti-angiogenic effects using curcumin correspond to combined PDE2 and PDE4 inhibition. Thromb Haemost. 2014; 113(2):319-28. DOI: 10.1160/TH14-05-0454. View

Konc J, Janezic D . ProBiS tools (algorithm, database, and web servers) for predicting and modeling of biologically interesting proteins. Prog Biophys Mol Biol. 2017; 128:24-32. DOI: 10.1016/j.pbiomolbio.2017.02.005. View

Mishra S, Palanivelu K . The effect of curcumin (turmeric) on Alzheimer's disease: An overview. Ann Indian Acad Neurol. 2009; 11(1):13-9. PMC: 2781139. DOI: 10.4103/0972-2327.40220. View

Ramirez S, Gomez-Valades A, Schneeberger M, Varela L, Haddad-Tovolli R, Altirriba J . Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control. Cell Metab. 2017; 25(6):1390-1399.e6. DOI: 10.1016/j.cmet.2017.05.010. View

Furlan V, Konc J, Bren U . Inverse Molecular Docking as a Novel Approach to Study Anticarcinogenic and Anti-Neuroinflammatory Effects of Curcumin. Molecules. 2018; 23(12). PMC: 6321024. DOI: 10.3390/molecules23123351. View

10.

Yang S, He X, Isaacs C, Dobkin C, Miller D, Philipp M . Roles of 17β-hydroxysteroid dehydrogenase type 10 in neurodegenerative disorders. J Steroid Biochem Mol Biol. 2014; 143:460-72. DOI: 10.1016/j.jsbmb.2014.07.001. View

11.

Ambrosio S, Majello B . Targeting Histone Demethylase LSD1/KDM1a in Neurodegenerative Diseases. J Exp Neurosci. 2018; 12:1179069518765743. PMC: 5863861. DOI: 10.1177/1179069518765743. View

12.

Navarro G, Martinez-Pinilla E, Sanchez-Melgar A, Ortiz R, Noe V, Martin M . A genomics approach identifies selective effects of trans-resveratrol in cerebral cortex neuron and glia gene expression. PLoS One. 2017; 12(4):e0176067. PMC: 5404873. DOI: 10.1371/journal.pone.0176067. View