Mitigating Aflatoxin Contamination in Groundnut Through A Combination of Genetic Resistance and Post-Harvest Management Practices

Overview

Journal Toxins (Basel)

Publisher MDPI

Specialty Toxicology

Date 2019 Jun 6

PMID 31163657

Citations 42

Authors

Manish K Pandey

Rakesh Kumar

Arun K Pandey

Pooja Soni

Sunil S Gangurde

Hari K Sudini

Jake C Fountain

Boshou Liao

Haile Desmae

Patrick Okori

Xiaoping Chen

Huifang Jiang

Venugopal Mendu

Hamidou Falalou

Samuel Njoroge

James Mwololo

Baozhu Guo

Weijian Zhuang

Xingjun Wang

Xuanqiang Liang

Rajeev K Varshney

Affiliations

Soon will be listed here.

Abstract

Aflatoxin is considered a "hidden poison" due to its slow and adverse effect on various biological pathways in humans, particularly among children, in whom it leads to delayed development, stunted growth, liver damage, and liver cancer. Unfortunately, the unpredictable behavior of the fungus as well as climatic conditions pose serious challenges in precise phenotyping, genetic prediction and genetic improvement, leaving the complete onus of preventing aflatoxin contamination in crops on post-harvest management. Equipping popular crop varieties with genetic resistance to aflatoxin is key to effective lowering of infection in farmer's fields. A combination of genetic resistance for in vitro seed colonization (IVSC), pre-harvest aflatoxin contamination (PAC) and aflatoxin production together with pre- and post-harvest management may provide a sustainable solution to aflatoxin contamination. In this context, modern "omics" approaches, including next-generation genomics technologies, can provide improved and decisive information and genetic solutions. Preventing contamination will not only drastically boost the consumption and trade of the crops and products across nations/regions, but more importantly, stave off deleterious health problems among consumers across the globe.

Citing Articles

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Antifungal Activity of , and Essential Oils against Isolated from Peanut Seeds.

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Factors influencing aflatoxin B1 levels in the groundnut ( L.) germplasm of Ethiopia.

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Aflatoxins in Peanut (): Prevalence, Global Health Concern, and Management from an Innovative Nanotechnology Approach: A Mechanistic Repertoire and Future Direction.

Sultana T, Malik K, Raja N, Mashwani Z, Hameed A, Ullah R ACS Omega. 2024; 9(24):25555-25574.

PMID: 38911815 PMC: 11190918. DOI: 10.1021/acsomega.4c01316.

Aspergillus flavus pangenome (AflaPan) uncovers novel aflatoxin and secondary metabolite associated gene clusters.

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