Spatiotemporal Optical Coherence (STOC) Manipulation Suppresses Coherent Cross-talk in Full-field Swept-source Optical Coherence Tomography

Overview

Journal Biomed Opt Express

Specialty Radiology

Date 2019 May 16

PMID 31086716

Citations 11

Authors

Dawid Borycki

Michal Hamkalo

Maciej Nowakowski

Maciej Szkulmowski

Maciej Wojtkowski

Affiliations

Soon will be listed here.

Abstract

Full-field swept-source optical coherence tomography (FF-SS-OCT) provides high-resolution depth-resolved images of the sample by parallel Fourier-domain interferometric detection. Although FF-SS-OCT implements high-speed volumetric imaging, it suffers from the cross-talk-generated noise from spatially coherent lasers. This noise reduces the transversal image resolution, which in turn, limits the wide adaptation of FF-SS-OCT for practical and clinical applications. Here, we introduce the novel spatiotemporal optical coherence (STOC) manipulation. In STOC the time-varying inhomogeneous phase masks are used to modulate the light incident on the sample. By properly adjusting these phase masks, the spatial coherence can be reduced. Consequently, the cross-talk-generated noise is suppressed, the transversal image resolution is improved by the factor of , and sample features become visible. STOC approach is validated by imaging 1951 USAF resolution test chart covered by the diffuser, scattering phantom and the rat skin . In all these cases STOC suppresses the cross-talk-generated noise, and importantly, do not compromise the transversal resolution. Thus, our method provides an enhancement of FF-SS-OCT that can be beneficial for imaging biological samples.

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