Knomics-Biota - a System for Exploratory Analysis of Human Gut Microbiota Data

Overview

Journal BioData Min

Publisher Biomed Central

Specialty Biology

Date 2018 Nov 20

PMID 30450127

Citations 18

Authors

Daria Efimova

Alexander Tyakht

Anna Popenko

Anatoly Vasilyev

Ilya Altukhov

Nikita Dovidchenko

Vera Odintsova

Natalya Klimenko

Robert Loshkarev

Maria Pashkova

Anna Elizarova

Viktoriya Voroshilova

Sergei Slavskii

Yury Pekov

Ekaterina Filippova

Tatiana Shashkova

Evgenii Levin

Dmitry Alexeev

Affiliations

Soon will be listed here.

Abstract

Background: Metagenomic surveys of human microbiota are becoming increasingly widespread in academic research as well as in food and pharmaceutical industries and clinical context. Intuitive tools for investigating experimental data are of high interest to researchers.

Results: Knomics-Biota is a web-based resource for exploratory analysis of human gut metagenomes. Users can generate and share analytical reports corresponding to common experimental schemes (like case-control study or paired comparison). Interactive visualizations and statistical analysis are provided in association with the external factors and in the context of thousands of publicly available datasets arranged into thematic collections. The web-service is available at https://biota.knomics.ru.

Conclusions: Knomics-Biota web service is a comprehensive tool for interactive metagenomic data analysis.

Citing Articles

Diet and the Gut Microbiome as Determinants Modulating Metabolic Outcomes in Young Obese Adults.

Livantsova E, Leonov G, Starodubova A, Varaeva Y, Vatlin A, Koshechkin S Biomedicines. 2024; 12(7).

PMID: 39062174 PMC: 11275099. DOI: 10.3390/biomedicines12071601.

Effect of Lactobacillus reuteri NCIMB 30351 drops on symptoms of infantile functional gastrointestinal disorders and gut microbiota in early infants: Results from a randomized, placebo-controlled clinical trial.

Tyrsin O, Tyrsin D, Nemenov D, Ruzov A, Odintsova V, Koshechkin S Eur J Pediatr. 2024; 183(5):2311-2324.

PMID: 38427038 DOI: 10.1007/s00431-024-05473-y.

Gut Microbiome in Post-COVID-19 Patients Is Linked to Immune and Cardiovascular Health Status but Not COVID-19 Severity.

Tkacheva O, Klimenko N, Kashtanova D, Tyakht A, Maytesyan L, Akopyan A Microorganisms. 2023; 11(4).

PMID: 37110459 PMC: 10144658. DOI: 10.3390/microorganisms11041036.

Luminal and Tumor-Associated Gut Microbiome Features Linked to Precancerous Lesions Malignancy Risk: A Compositional Approach.

Romanov V, Karasev I, Klimenko N, Koshechkin S, Tyakht A, Malikhova O Cancers (Basel). 2022; 14(21).

PMID: 36358626 PMC: 9653741. DOI: 10.3390/cancers14215207.

The hallmarks of dietary intervention-resilient gut microbiome.

Klimenko N, Odintsova V, Revel-Muroz A, Tyakht A NPJ Biofilms Microbiomes. 2022; 8(1):77.

PMID: 36209276 PMC: 9547895. DOI: 10.1038/s41522-022-00342-8.

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