Label-Free Monitoring of Diffusion in Microfluidics

Overview

Journal Micromachines (Basel)

Publisher MDPI

Date 2018 Nov 8

PMID 30400519

Citations 3

Authors

Kristian Tolbol Sorensen

Anders Kristensen

Affiliations

Soon will be listed here.

Abstract

Label-free, real-time detection of concentration gradients is demonstrated in a microfluidic H-filter, using an integrated photonic crystal slab sensor to monitor sample refractive index with spatial resolution. The recorded diffusion profiles reveal root-mean-square diffusion lengths for non-fluorescing and non-absorbing molecules, both small (glucose, 180 Da) and large (bovine serum albumin, 67 kDa).

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