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A Regeneration Toolkit

Overview
Journal Dev Cell
Publisher Cell Press
Date 2018 Nov 7
PMID 30399333
Citations 26
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Abstract

The ability of animals to replace injured body parts has been a subject of fascination for centuries. The emerging importance of regenerative medicine has reinvigorated investigations of innate tissue regeneration, and the development of powerful genetic tools has fueled discoveries into how tissue regeneration occurs. Here, we present an overview of the armamentarium employed to probe regeneration in vertebrates, highlighting areas where further methodology advancement will deepen mechanistic findings.

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References
1.
Roy S, Gardiner D, Bryant S . Vaccinia as a tool for functional analysis in regenerating limbs: ectopic expression of Shh. Dev Biol. 2000; 218(2):199-205. DOI: 10.1006/dbio.1999.9556. View

2.
Newmark P, Sanchez Alvarado A . Bromodeoxyuridine specifically labels the regenerative stem cells of planarians. Dev Biol. 2001; 220(2):142-53. DOI: 10.1006/dbio.2000.9645. View

3.
Vihtelic T, Hyde D . Light-induced rod and cone cell death and regeneration in the adult albino zebrafish (Danio rerio) retina. J Neurobiol. 2000; 44(3):289-307. DOI: 10.1002/1097-4695(20000905)44:3<289::aid-neu1>3.0.co;2-h. View

4.
Poss K, Nechiporuk A, Hillam A, Johnson S, Keating M . Mps1 defines a proximal blastemal proliferative compartment essential for zebrafish fin regeneration. Development. 2002; 129(22):5141-9. DOI: 10.1242/dev.129.22.5141. View

5.
Yan Z, Choi S, Liu X, Zhang M, Schageman J, Lee S . Highly coordinated gene regulation in mouse skeletal muscle regeneration. J Biol Chem. 2002; 278(10):8826-36. DOI: 10.1074/jbc.M209879200. View