Characterization of a Novel Member of the Family Caulimoviridae Infecting Dioscorea Nummularia in the Pacific, Which May Represent a New Genus of DsDNA Plant Viruses

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2018 Sep 13

PMID 30208072

Citations 5

Authors

Amit C Sukal

Dawit B Kidanemariam

James L Dale

Robert M Harding

Anthony P James

Affiliations

Soon will be listed here.

Abstract

We have characterized the complete genome of a novel circular double-stranded DNA virus, tentatively named Dioscorea nummularia-associated virus (DNUaV), infecting Dioscorea nummularia originating from Samoa. The genome of DNUaV comprised 8139 bp and contained four putative open reading frames (ORFs). ORFs 1 and 2 had no identifiable conserved domains, while ORF 3 had conserved motifs typical of viruses within the family Caulimoviridae including coat protein, movement protein, aspartic protease, reverse transcriptase and ribonuclease H. A transactivator domain, similar to that present in members of several caulimoviridae genera, was also identified in the putative ORF 4. The genome size, organization, and presence of conserved amino acid domains are similar to other viruses in the family Caulimoviridae. However, based on nucleotide sequence similarity and phylogenetic analysis, DNUaV appears to be a distinct novel member of the family and may represent a new genus.

Citing Articles

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