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MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets

Overview
Journal Mol Biol Evol
Publisher Oxford University Press
Specialty Biology
Date 2016 Mar 24
PMID 27004904
Citations 16135
Authors
Sudhir Kumar
Glen Stecher
Koichiro Tamura
Affiliations
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Abstract

We present the latest version of the Molecular Evolutionary Genetics Analysis (Mega) software, which contains many sophisticated methods and tools for phylogenomics and phylomedicine. In this major upgrade, Mega has been optimized for use on 64-bit computing systems for analyzing larger datasets. Researchers can now explore and analyze tens of thousands of sequences in Mega The new version also provides an advanced wizard for building timetrees and includes a new functionality to automatically predict gene duplication events in gene family trees. The 64-bit Mega is made available in two interfaces: graphical and command line. The graphical user interface (GUI) is a native Microsoft Windows application that can also be used on Mac OS X. The command line Mega is available as native applications for Windows, Linux, and Mac OS X. They are intended for use in high-throughput and scripted analysis. Both versions are available from www.megasoftware.net free of charge.

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References
1.
Hedges S, Marin J, Suleski M, Paymer M, Kumar S . Tree of life reveals clock-like speciation and diversification. Mol Biol Evol. 2015; 32(4):835-45. PMC: 4379413. DOI: 10.1093/molbev/msv037. View
2.
Kumar S, Stecher G, Peterson D, Tamura K . MEGA-CC: computing core of molecular evolutionary genetics analysis program for automated and iterative data analysis. Bioinformatics. 2012; 28(20):2685-6. PMC: 3467750. DOI: 10.1093/bioinformatics/bts507. View
3.
Yilmaz P, Parfrey L, Yarza P, Gerken J, Pruesse E, Quast C . The SILVA and "All-species Living Tree Project (LTP)" taxonomic frameworks. Nucleic Acids Res. 2013; 42(Database issue):D643-8. PMC: 3965112. DOI: 10.1093/nar/gkt1209. View
4.
Quast C, Pruesse E, Yilmaz P, Gerken J, Schweer T, Yarza P . The SILVA ribosomal RNA gene database project: improved data processing and web-based tools. Nucleic Acids Res. 2012; 41(Database issue):D590-6. PMC: 3531112. DOI: 10.1093/nar/gks1219. View
5.
Kumar S, Tamura K, Nei M . MEGA: Molecular Evolutionary Genetics Analysis software for microcomputers. Comput Appl Biosci. 1994; 10(2):189-91. DOI: 10.1093/bioinformatics/10.2.189. View