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Liquid Biopsy in Prostate Cancer: Circulating Tumor Cells and Beyond

Overview
Publisher Springer
Specialties Oncology
Pharmacology
Date 2018 Sep 1
PMID 30168118
Citations 12
Authors
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Abstract

Prostate cancer is a common malignancy impacting countless men without curative options in the advanced state. Numerous therapies have been introduced in recent years improving survival and symptom control, yet optimal methods for predicting or monitoring response have not been developed. In the era of precision medicine, characterization of individual cancers is necessary to inform treatment decisions. Liquid biopsies, through evaluation of various blood-based analytes, provide a method of patient evaluation with potential applications in virtually all disease states. In this review, we will describe current approaches with a particular focus on demonstrated clinical utility in the evaluation and management of prostate cancer.

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