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Single-Cell Transcriptomic Analysis of Tumor Heterogeneity

Overview
Journal Trends Cancer
Publisher Cell Press
Specialty Oncology
Date 2018 Apr 3
PMID 29606308
Citations 76
Authors
Hanna Mendes Levitin
Jinzhou Yuan
Peter A Sims
Affiliations
Soon will be listed here.
Abstract

Intratumoral heterogeneity is among the greatest challenges in precision cancer therapy. However, developments in high-throughput single-cell RNA sequencing (scRNA-seq) may now provide the statistical power to dissect the diverse cellular populations of tumors. In the future these technologies might inform the selection of targeted combination therapies and enrollment criteria for clinical trials.

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