Detection of Migrasomes
Overview
Affiliations
The migrasome is a newly discovered, migration-dependent membrane-bound cellular organelle. It functions in the active release of intracellular contents into the external environment and in cell-cell communications. Migrasomes have characteristic morphological features compared with intracellular organelles and extracellular vesicles. This unit describes methods for visualizing migrasomes by fluorescence microscopy and electron microscopy.
Liu X, Jiao H, Zhang B, Zhang S, Yan K, Qu J Life Med. 2025; 2(6):lnad050.
PMID: 39872064 PMC: 11749555. DOI: 10.1093/lifemedi/lnad050.
Quantification of urinary podocyte-derived migrasomes for the diagnosis of kidney disease.
Yang R, Zhang H, Chen S, Lou K, Zhou M, Zhang M J Extracell Vesicles. 2024; 13(6):e12460.
PMID: 38853287 PMC: 11162892. DOI: 10.1002/jev2.12460.
Novel insights into the roles of migrasome in cancer.
Deng S, Wu Y, Huang S, Yang X Discov Oncol. 2024; 15(1):166.
PMID: 38748047 PMC: 11096295. DOI: 10.1007/s12672-024-00942-0.
Migrasomes and tetraspanins in hepatocellular carcinoma: current status and future prospects.
Zhang Z, Zhang T, Zhang R, Zhang Z, Tan S Future Sci OA. 2023; 9(9):FSO890.
PMID: 37752917 PMC: 10518826. DOI: 10.2144/fsoa-2023-0086.
Li T, Su X, Lu P, Kang X, Hu M, Li C Adv Sci (Weinh). 2023; 10(22):e2206432.
PMID: 37246283 PMC: 10401184. DOI: 10.1002/advs.202206432.