» Articles » PMID: 29525989

Detection of Migrasomes

Overview
Specialty Molecular Biology
Date 2018 Mar 12
PMID 29525989
Citations 11
Authors
Affiliations
Soon will be listed here.
Abstract

The migrasome is a newly discovered, migration-dependent membrane-bound cellular organelle. It functions in the active release of intracellular contents into the external environment and in cell-cell communications. Migrasomes have characteristic morphological features compared with intracellular organelles and extracellular vesicles. This unit describes methods for visualizing migrasomes by fluorescence microscopy and electron microscopy.

Citing Articles

Migrasomes trigger innate immune activation and mediate transmission of senescence signals across human cells.

Liu X, Jiao H, Zhang B, Zhang S, Yan K, Qu J Life Med. 2025; 2(6):lnad050.

PMID: 39872064 PMC: 11749555. DOI: 10.1093/lifemedi/lnad050.


Quantification of urinary podocyte-derived migrasomes for the diagnosis of kidney disease.

Yang R, Zhang H, Chen S, Lou K, Zhou M, Zhang M J Extracell Vesicles. 2024; 13(6):e12460.

PMID: 38853287 PMC: 11162892. DOI: 10.1002/jev2.12460.


Novel insights into the roles of migrasome in cancer.

Deng S, Wu Y, Huang S, Yang X Discov Oncol. 2024; 15(1):166.

PMID: 38748047 PMC: 11096295. DOI: 10.1007/s12672-024-00942-0.


Migrasomes and tetraspanins in hepatocellular carcinoma: current status and future prospects.

Zhang Z, Zhang T, Zhang R, Zhang Z, Tan S Future Sci OA. 2023; 9(9):FSO890.

PMID: 37752917 PMC: 10518826. DOI: 10.2144/fsoa-2023-0086.


Bone Marrow Mesenchymal Stem Cell-Derived Dermcidin-Containing Migrasomes enhance LC3-Associated Phagocytosis of Pulmonary Macrophages and Protect against Post-Stroke Pneumonia.

Li T, Su X, Lu P, Kang X, Hu M, Li C Adv Sci (Weinh). 2023; 10(22):e2206432.

PMID: 37246283 PMC: 10401184. DOI: 10.1002/advs.202206432.


References
1.
Ma L, Li Y, Peng J, Wu D, Zhao X, Cui Y . Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration. Cell Res. 2014; 25(1):24-38. PMC: 4650581. DOI: 10.1038/cr.2014.135. View

2.
da Rocha-Azevedo B, Schmid S . Migrasomes: a new organelle of migrating cells. Cell Res. 2014; 25(1):1-2. PMC: 4650585. DOI: 10.1038/cr.2014.146. View

3.
TRAMS E, Lauter C, Salem Jr N, Heine U . Exfoliation of membrane ecto-enzymes in the form of micro-vesicles. Biochim Biophys Acta. 1981; 645(1):63-70. DOI: 10.1016/0005-2736(81)90512-5. View

4.
Johnstone R, Adam M, Hammond J, Orr L, Turbide C . Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). J Biol Chem. 1987; 262(19):9412-20. View

5.
Kowal J, Tkach M, Thery C . Biogenesis and secretion of exosomes. Curr Opin Cell Biol. 2014; 29:116-25. DOI: 10.1016/j.ceb.2014.05.004. View