In Vitro Activity of Imipenem Against Enterococci and Staphylococci and Evidence for High Rates of Synergism with Teicoplanin, Fosfomycin, and Rifampin

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 1986 Nov 1

PMID 2948444

Citations 11

Authors

E Debbia

P E Varaldo

G C Schito

Affiliations

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Abstract

The in vitro activities of imipenem alone and in combination with teicoplanin, fosfomycin, and rifampin were tested against clinical isolates of enterococci and staphylococci. In both groups of organisms, the three combinations demonstrated high rates of synergism in both checkerboard and time-kill studies.

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