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In Vitro Activity of LY146032 Alone and in Combination with Other Antibiotics Against Gram-positive Bacteria

Overview
Journal Antimicrob Agents Chemother
Publisher American Society for Microbiology
Specialty Pharmacology
Date 1988 Feb 1
PMID 2834999
Citations 19
Authors
E Debbia
A Pesce
G C Schito
Affiliations
Soon will be listed here.
Abstract

The antibacterial activity of LY146032 alone and in combination with other drugs was assayed against gram-positive isolates. Synergism was found when LY146032 was combined with netilmicin, amikacin, imipenem, and fosfomycin by both checkerboard and time-kill tests. Indifference predominated when LY146032 was combined with teicoplanin, vancomycin, and rifampin. Under no circumstances and with no combinations was an antagonistic effect detected.

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