Autonomy Declared by Primary Cilia Through Compartmentalization of Membrane Phosphoinositides

Overview

Journal Curr Opin Cell Biol

Publisher Elsevier

Specialty Cell Biology

Date 2018 Feb 25

PMID 29477020

Citations 10

Authors

Siew Cheng Phua

Yuta Nihongaki

Takanari Inoue

Affiliations

Soon will be listed here.

Abstract

The primary cilium is a cell surface projection from plasma membrane which transduces external stimuli to diverse signaling pathways. To function as an independent signaling organelle, the molecular composition of the ciliary membrane has to be distinct from that of the plasma membrane. Here, we review recent findings which have deepened our understanding of the unique yet dynamic phosphoinositide profile found in the primary cilia.

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