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A Phosphoinositide Code for Primary Cilia

Overview
Journal Dev Cell
Publisher Cell Press
Date 2015 Aug 26
PMID 26305588
Citations 24
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Abstract

How phosphoinositide metabolism is coupled to primary cilia physiology is poorly understood. Reporting recently in Developmental Cell, Chávez et al. (2015) and Garcia-Gonzalo et al. (2015) show that INPP5E-mediated phosphoinositide metabolism, which creates a specific phosphoinositide distribution, ensures proper protein trafficking and Hh signaling in primary cilia.

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