» Articles » PMID: 29045

Dihydrofolate Reductase from Lactobacillus Casei. X-ray Structure of the Enzyme Methotrexate.NADPH Complex

Overview
Journal J Biol Chem
Specialty Biochemistry
Date 1978 Oct 10
PMID 29045
Citations 18
Authors
Affiliations
Soon will be listed here.
Citing Articles

The impact of the human gut microbiome on the treatment of autoimmune disease.

Nayak R, Orellana D Immunol Rev. 2024; 325(1):107-130.

PMID: 38864582 PMC: 11338731. DOI: 10.1111/imr.13358.


Albumin-Methotrexate Prodrug Analogues That Undergo Intracellular Reactivation Following Entrance into Cancerous Glioma Cells.

Cooper I, Schnaider-Beeri M, Fridkin M, Shechter Y Pharmaceutics. 2022; 14(1).

PMID: 35056966 PMC: 8778984. DOI: 10.3390/pharmaceutics14010071.


Design and in vitro validation of multivalent dendrimer methotrexates as a folate-targeting anticancer therapeutic.

Thomas T, Joice M, Sumit M, Silpe J, Kotlyar A, Bharathi S Curr Pharm Des. 2013; 19(37):6594-605.

PMID: 23621534 PMC: 3859140. DOI: 10.2174/1381612811319370004.


Polyvalent dendrimer-methotrexate as a folate receptor-targeted cancer therapeutic.

Thomas T, Huang B, Choi S, Silpe J, Kotlyar A, Desai A Mol Pharm. 2012; 9(9):2669-2676.

PMID: 22827500 PMC: 4457335. DOI: 10.1021/mp3002232.


Selectivity analysis of 5-(arylthio)-2,4-diaminoquinazolines as inhibitors of Candida albicans dihydrofolate reductase by molecular dynamics simulations.

Gokhale V, Kulkarni V J Comput Aided Mol Des. 2000; 14(5):495-506.

PMID: 10896321 DOI: 10.1023/a:1008189724803.