Evaluation of Keratocystic Odontogenic Tumors Using Cone Beam Computed Tomography

Overview

Journal J Istanb Univ Fac Dent

Specialty Dentistry

Date 2017 Sep 29

PMID 28955573

Citations 1

Authors

Mustafa Gumusok

Meryem Toraman Alkurt

Farid Museyibov

Ozlem Ucok

Affiliations

Soon will be listed here.

Abstract

Purpose: The aim of this retrospective study is to determine the radiological features of keratocystic odontogenic tumors (KCOT) using cone-beam computed tomography (CBCT).

Materials And Methods: CBCT images of 28 patients who had histopathologically-confirmed KCOT were retrospectively reviewed from the archives of the Department of Dentomaxillofacial Radiology, Gazi University Faculty of Dentistry. The location and size of KCOT, cortical expansion, cortical perforation, relation with the impacted teeth, and the impact on the mandibular canal were evaluated.

Results: The mean age of patients at initial diagnosis was 34.5 years. Patients with an impacted tooth were significantly younger than those without an impacted tooth (p<0.05). Among KCOTs, 21% were localized in the maxilla whereas 79% were found in the mandible. The lesions localized in the mandible were mostly found in the retromolar-ramus region. Of these patients, 93% had cortical expansion and 75% had bone perforation. Of the 22 mandibular lesions, 20 were in close proximity of the mandibular canal and 18 (90%) of these lesions had caused destruction in the mandibular canal.

Conclusion: KCOTs exhibit their aggressive nature in the jaw bone. CBCT is a useful radiological imaging method to examine the radiologic characteristics of KCOTs such as bone destruction and their spatial relations with the neighboring anatomic structures.

Citing Articles

Comparison of computed tomographic findings for radiolucent lesions of the mandibular ameloblastoma, odontogenic keratocyst, dentigerous cyst, and simple bone cyst.

Sueyoshi T, Sameshima J, Kaneko N, Chikui T, Chen H, Yokomizo S J Dent Sci. 2025; 20(1):605-612.

PMID: 39873068 PMC: 11762212. DOI: 10.1016/j.jds.2024.04.013.

An Insight Into the Effect of Odontogenic Keratocysts on Surrounding Structures: Cone-Beam Computed Tomography-Based Analysis of Cases.

Ac V, Parihar A, Saxena A Cureus. 2023; 15(6):e40488.

PMID: 37461795 PMC: 10349913. DOI: 10.7759/cureus.40488.

References

MacDonald-Jankowski D . Keratocystic odontogenic tumour: systematic review. Dentomaxillofac Radiol. 2010; 40(1):1-23. PMC: 3611466. DOI: 10.1259/dmfr/29949053. View

Scarfe W, Farman A, Sukovic P . Clinical applications of cone-beam computed tomography in dental practice. J Can Dent Assoc. 2006; 72(1):75-80. View

Myoung H, Hong S, Hong S, Lee J, Lim C, Choung P . Odontogenic keratocyst: Review of 256 cases for recurrence and clinicopathologic parameters. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001; 91(3):328-33. DOI: 10.1067/moe.2001.113109. View

Monsour P, Dudhia R . Implant radiography and radiology. Aust Dent J. 2008; 53 Suppl 1:S11-25. DOI: 10.1111/j.1834-7819.2008.00037.x. View

Zhao Y, Liu B, Cheng G, Wang S, Wang Y . Recurrent keratocystic odontogenic tumours: report of 19 cases. Dentomaxillofac Radiol. 2012; 41(2):96-102. PMC: 3520371. DOI: 10.1259/dmfr/22891281. View

Scarfe W, Farman A . What is cone-beam CT and how does it work?. Dent Clin North Am. 2008; 52(4):707-30, v. DOI: 10.1016/j.cden.2008.05.005. View

Brannon R . The odontogenic keratocyst. A clinicopathologic study of 312 cases. Part I. Clinical features. Oral Surg Oral Med Oral Pathol. 1976; 42(1):54-72. DOI: 10.1016/0030-4220(76)90031-1. View

Dammer R, Niederdellmann H, Dammer P . Conservative or radical treatment of keratocysts: a retrospective review. Br J Oral Maxillofac Surg. 1997; 35(1):46-8. DOI: 10.1016/s0266-4356(97)90009-7. View

Agaram N, Collins B, Barnes L, Lomago D, Aldeeb D, Swalsky P . Molecular analysis to demonstrate that odontogenic keratocysts are neoplastic. Arch Pathol Lab Med. 2004; 128(3):313-7. DOI: 10.5858/2004-128-313-MATDTO. View

10.

Maurette P, Jorge J, de Moraes M . Conservative treatment protocol of odontogenic keratocyst: a preliminary study. J Oral Maxillofac Surg. 2006; 64(3):379-83. DOI: 10.1016/j.joms.2005.11.007. View

11.

MacDonald-Jankowski D, Li T . Keratocystic odontogenic tumour in a Hong Kong community: the clinical and radiological features. Dentomaxillofac Radiol. 2010; 39(3):167-75. PMC: 3520223. DOI: 10.1259/dmfr/30802198. View

12.

Haring J, Van Dis M . Odontogenic keratocysts: a clinical, radiographic, and histopathologic study. Oral Surg Oral Med Oral Pathol. 1988; 66(1):145-53. DOI: 10.1016/0030-4220(88)90082-5. View

13.

Kocak-Berberoglu H, Cakarer S, Brkic A, Gurkan-Koseoglu B, Altug-Aydil B, Keskin C . Three-dimensional cone-beam computed tomography for diagnosis of keratocystic odontogenic tumours; evaluation of four cases. Med Oral Patol Oral Cir Bucal. 2012; 17(6):e1000-5. PMC: 3505693. DOI: 10.4317/medoral.17629. View

14.

Titinchi F, Nortje C . Keratocystic odontogenic tumor: a recurrence analysis of clinical and radiographic parameters. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012; 114(1):136-42. DOI: 10.1016/j.oooo.2012.01.032. View

15.

Blanchard S . Odontogenic keratocysts: review of the literature and report of a case. J Periodontol. 1997; 68(3):306-11. DOI: 10.1902/jop.1997.68.3.306. View

16.

Kaneda T, Minami M, Kurabayashi T . Benign odontogenic tumors of the mandible and maxilla. Neuroimaging Clin N Am. 2003; 13(3):495-507. DOI: 10.1016/s1052-5149(03)00032-7. View

17.

Stoelinga P . Long-term follow-up on keratocysts treated according to a defined protocol. Int J Oral Maxillofac Surg. 2001; 30(1):14-25. DOI: 10.1054/ijom.2000.0027. View

18.

Barreto D, Gomez R, Bale A, Boson W, De Marco L . PTCH gene mutations in odontogenic keratocysts. J Dent Res. 2000; 79(6):1418-22. DOI: 10.1177/00220345000790061101. View

19.

Brauer H, Diaz C, Manegold-Brauer G . Radiographic assessment of a keratocystic odontogenic tumour using cone-beam computed tomography. Eur Arch Paediatr Dent. 2013; 14(3):173-7. DOI: 10.1007/s40368-013-0030-y. View

20.

Ba K, Li X, Wang H, Liu Y, Zheng G, Yang Z . Correlation between imaging features and epithelial cell proliferation in keratocystic odontogenic tumour. Dentomaxillofac Radiol. 2010; 39(6):368-74. PMC: 3520243. DOI: 10.1259/dmfr/27538271. View